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美国印第安人和西班牙裔人群获得肾移植的情况。

Access to renal transplantation among American Indians and Hispanics.

作者信息

Sequist Thomas D, Narva Andrew S, Stiles Sharon K, Karp Shelley K, Cass Alan, Ayanian John Z

机构信息

Department of Health Care Policy, Harvard Medical School, Boston, MA, USA.

出版信息

Am J Kidney Dis. 2004 Aug;44(2):344-52. doi: 10.1053/j.ajkd.2004.04.039.

Abstract

BACKGROUND

African Americans have decreased access to renal transplantation compared with whites. Whether similar barriers exist for American Indians or Hispanics is not well defined.

METHODS

The authors identified a total of 1,335 patients ages 20 to 59 years without prior renal transplantation undergoing dialysis in December 1994 in Arizona and New Mexico. For each patient, information was collected on identification as a potential candidate for renal transplantation, referral to a renal transplantation center, completion of 4 stages in the evaluation process, and receipt of a transplant over 7 years.

RESULTS

American Indians were more likely than whites to be identified as potential candidates (relative risk [RR] 1.30, 95% confidence interval [CI] 1.15 to 1.44) and to be referred to a transplant center (RR 1.16, 95% CI 1.09 to 1.19). There were no significant differences in candidacy or referral status between Hispanics and whites. Among potential candidates referred to a transplant center, both American Indians (RR 0.73, 95% CI 0.51 to 0.96) and Hispanics (RR 0.68, 95% CI 0.50 to 0.88) were less likely than whites to be placed on a waiting list. Both American Indians (hazard ratio [HR] 0.37, 95% CI 0.24 to 0.58) and Hispanics (HR 0.58, 95% CI 0.39 to 0.86) were much less likely than whites to undergo renal transplantation.

CONCLUSION

Despite similar referral rates for renal transplantation, American Indians and Hispanics were less likely than whites to be placed on a transplant waiting list or receive a transplant. Policies to address these disparities should address specific barriers within the transplant evaluation process.

摘要

背景

与白人相比,非裔美国人接受肾移植的机会较少。美国印第安人或西班牙裔人群是否存在类似的障碍尚不清楚。

方法

作者确定了1994年12月在亚利桑那州和新墨西哥州接受透析且年龄在20至59岁之间、此前未接受过肾移植的1335名患者。收集了每位患者作为肾移植潜在候选人的认定信息、转诊至肾移植中心的信息、评估过程中4个阶段的完成情况以及7年多来接受移植的情况。

结果

美国印第安人比白人更有可能被认定为潜在候选人(相对风险[RR]为1.30,95%置信区间[CI]为1.15至1.44)并被转诊至移植中心(RR为1.16,95%CI为1.09至1.19)。西班牙裔和白人在候选资格或转诊状态方面没有显著差异。在被转诊至移植中心的潜在候选人中,美国印第安人(RR为0.73,95%CI为0.51至0.96)和西班牙裔(RR为0.68,95%CI为0.50至0.88)被列入等候名单的可能性均低于白人。美国印第安人(风险比[HR]为0.37,95%CI为0.24至0.58)和西班牙裔(HR为0.58,95%CI为0.39至0.86)接受肾移植的可能性均远低于白人。

结论

尽管肾移植的转诊率相似,但美国印第安人和西班牙裔被列入移植等候名单或接受移植的可能性低于白人。解决这些差异的政策应针对移植评估过程中的具体障碍。

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