Cirignotta F
Unit of Neurology, S. Orsola-Malpighi Hospital, University of Bologna, Via Albertoni 15, 40138 Bologna, Italy.
Minerva Med. 2004 Jun;95(3):177-85.
Growing interest in sleep disorders has led to increased research in this direction. Increasingly sophisticated instrumental tests have disclosed new breathing patterns and complex syndromes. The initial identification of obstructive apneas was followed by studies characterizing snoring, hypopneas, respiratory effort-related arousal and flow limitation events. Since Pickwickian syndrome, an historical term currently deemed obsolete and confusing, sleep investigations have differentiated secondary hypoventilation, central hypoventilation and syndromes resulting from narrowing of the upper airways (snoring, upper airway resistance syndrome, obstructive sleep apnea-hypopnea syndrome). Inevitably, this has given rise to some confusion in the classification of events and syndromes which recent studies have attempted to clarify.
对睡眠障碍日益增长的兴趣促使在这一方向上的研究不断增加。日益精密的仪器测试揭示了新的呼吸模式和复杂的综合征。在阻塞性呼吸暂停最初被识别之后,开展了一系列研究,对打鼾、呼吸浅慢、与呼吸努力相关的觉醒以及气流受限事件进行了特征描述。自匹克威克综合征(一个目前被认为过时且容易混淆的历史术语)以来,睡眠研究已经区分了继发性通气不足、中枢性通气不足以及由上呼吸道狭窄导致的综合征(打鼾、上气道阻力综合征、阻塞性睡眠呼吸暂停低通气综合征)。不可避免地,这在事件和综合征的分类方面引发了一些混乱,近期的研究试图对此加以澄清。