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鼾症及轻中度阻塞性睡眠呼吸暂停低通气综合征患者的临床特征。

Peculiarities of clinical profile of snoring and mild to moderate obstructive sleep apnea-hypopnea syndrome patients.

机构信息

Department of Otolaryngology, Medical Academy of Lithuanian University of Health Sciences, Kaunas, Lithuania.

出版信息

Sleep Breath. 2012 Sep;16(3):835-43. doi: 10.1007/s11325-011-0584-z. Epub 2011 Sep 3.

DOI:10.1007/s11325-011-0584-z
PMID:21887611
Abstract

PURPOSE

The purpose of this study is to perform comprehensive evaluation of the snoring and mild to moderate obstructive sleep apnea-hypopnea syndrome (OSAHS) patients for their anatomical, functional, and psychoemotional clinical properties.

METHODS

Seventy-four snoring patients, aged 24 to 64 (mean 41.83 ± 11.01) years underwent full-night polysomnography, nasopharyngoscopy, and Mueller maneuver. Clinical tests battery consisting of visual analogue scales (VAS) scales, Lithuanian version of Sleep Apnea Quality of Life Index (SAQLI-LT), Spielberg's State-Trait Anxiety Inventory (STAI), Beck Depression Inventory-Second Edition (BDI-II), and Epworth Sleepiness Scale (ESS) were applied to assess their distinctive clinical properties.

RESULTS

The total group of snoring and mild to moderate OSAHS patients presented with considerably enlarged VAS snoring and daytime sleepiness scores (mean 66.32 ± 19.07 and 35.03 ± 27.83 points), mild BDI-II scores (mean 10.96 ± 9.42 points), and moderate trait anxiety scores (mean 41.51 ± 8.62 points). All the scores of daytime complaints measured with the VAS correlated statistically significantly with the mean scores of the ESS, SAQLI-LT, trait anxiety, and BDI-II. Both groups, of snoring and mild to moderate OSAHS patients, indicated similar intensity of the major complaints according to the VAS, same as similar BDI-II, STAI, and SAQLI-LT scores. A higher Friedman's score of palatal tonsils was found in the group of snoring patients, comparing to that of the group of mild to moderate OSAHS patients (p < 0.05).

CONCLUSIONS

Snoring and mild to moderate OSAHS patients have resemblances in their distinctive anatomical and clinical properties. This group of the patients revealed mild depression and moderate trait anxiety scores when measured with the BDI-II and STAI, which correlated significantly with the severity of the patients' daytime complaints measured with the VAS.

摘要

目的

本研究旨在全面评估打鼾和轻中度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的解剖、功能和心理情绪临床特征。

方法

74 例打鼾患者,年龄 24 至 64 岁(平均 41.83 ± 11.01 岁),行整夜多导睡眠图、鼻咽镜和 Mueller 动作检查。应用视觉模拟量表(VAS)、立陶宛版睡眠呼吸暂停生活质量指数(SAQLI-LT)、斯皮尔伯格状态-特质焦虑量表(STAI)、贝克抑郁量表第二版(BDI-II)和 Epworth 嗜睡量表(ESS)等临床测试量表评估其独特的临床特征。

结果

打鼾和轻中度 OSAHS 患者总组的 VAS 打鼾和日间嗜睡评分(分别为 66.32 ± 19.07 和 35.03 ± 27.83 分)、轻度 BDI-II 评分(平均 10.96 ± 9.42 分)和中度特质焦虑评分(平均 41.51 ± 8.62 分)均较高。VAS 测量的日间主诉评分均与 ESS、SAQLI-LT、特质焦虑和 BDI-II 的平均评分呈统计学显著相关。打鼾和轻中度 OSAHS 患者两组均根据 VAS 报告了相似强度的主要主诉,BDI-II、STAI 和 SAQLI-LT 评分也相似。与轻中度 OSAHS 患者组相比,打鼾患者组的软腭扁桃体 Friedman 评分更高(p < 0.05)。

结论

打鼾和轻中度 OSAHS 患者在其独特的解剖和临床特征上具有相似性。该组患者在 BDI-II 和 STAI 中表现出轻度抑郁和中度特质焦虑评分,与 VAS 测量的患者日间主诉严重程度显著相关。

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