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模仿滑膜炎、痤疮、脓疱病、骨肥厚和骨炎(SAPHO)综合征的B族链球菌菌血症

Group B Streptococcus Bacteremia Mimicking Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome.

作者信息

Fukuzawa Fumitoshi, Uehara Takanori, Yamashita Shiho, Hayashi Yasushi, Ikusaka Masatomi

机构信息

General Medicine, Chiba University Hospital, Chiba, JPN.

出版信息

Cureus. 2022 Jul 29;14(7):e27468. doi: 10.7759/cureus.27468. eCollection 2022 Jul.

DOI:10.7759/cureus.27468
PMID:36060405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9421099/
Abstract

Group B (GBS) causes septic arthritis in healthy adults, and a significant number of GBS septic arthritis cases involve multiple joints. Nevertheless, septic arthritis is commonly monoarticular. Here, we report a case of a 45-year-old man who complained of subacute fever and right shoulder and right buttock pain for three weeks despite undergoing garenoxacin treatment for one week. Although synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome could be a possible differential diagnosis for this patient, the fever and subacute clinical course could not be explained. Blood cultures revealed the presence of GBS; therefore, he was diagnosed with septic arthritis. After antibiotic treatment for six weeks, his symptoms resolved.

摘要

B组链球菌(GBS)可导致健康成年人发生脓毒性关节炎,且相当数量的GBS脓毒性关节炎病例累及多个关节。然而,脓毒性关节炎通常为单关节发病。在此,我们报告一例45岁男性患者,尽管接受了一周的加替沙星治疗,但仍主诉亚急性发热以及右肩和右臀部疼痛三周。虽然滑膜炎、痤疮、脓疱病、骨肥厚和骨炎(SAPHO)综合征可能是该患者的一个鉴别诊断,但发热和亚急性临床病程无法用该综合征解释。血培养显示存在GBS;因此,他被诊断为脓毒性关节炎。经过六周的抗生素治疗后,他的症状得到缓解。

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