Giusiano G E, Mangiaterra M, Rojas F, Gómez V
Departamento Micología, Instituto de Medicina Regional, Universidad Nacional del Nordeste, Resistencia, Argentina.
Mycoses. 2004 Aug;47(7):300-3. doi: 10.1111/j.1439-0507.2004.00993.x.
The aim of this study was to determine the distribution and antifungal susceptibility profile of yeast species isolated from neonates in Neonatal Intensive Care Units (NICU) in northeast of Argentina. With this purpose 92 strains isolated from 25 blood stream cultures, 20 venous catheters, 23 suprapubic aspirations and 24 rectal swabs were studied. Candida albicans and C. parapsilosis appeared with similar frequencies (36%) in blood stream isolates. Candida parapsilosis (50%) was the most frequent catheters colonizer and C. tropicalis (54.2%) was the most frequent yeast associated with gastrointestinal tract colonization. Candida krusei, C. glabrata and Trichosporon cutaneum appeared with a very low frequency. A high rate of susceptibility to amphotericin B, fluconazole, and itraconazole was observed.
本研究的目的是确定从阿根廷东北部新生儿重症监护病房(NICU)的新生儿中分离出的酵母菌种的分布及其抗真菌药敏谱。为此,对从25份血培养物、20根静脉导管、23份耻骨上穿刺物和24份直肠拭子中分离出的92株菌株进行了研究。白色念珠菌和近平滑念珠菌在血培养分离株中的出现频率相似(36%)。近平滑念珠菌(50%)是最常见的导管定植菌,热带念珠菌(54.2%)是与胃肠道定植相关的最常见酵母菌种。克柔念珠菌、光滑念珠菌和皮状丝孢酵母的出现频率很低。观察到对两性霉素B、氟康唑和伊曲康唑的高敏感率。