Boyd J W
Virginia Maryland Regional College of Veterinary Medicine, Division of Pathobiology and Public Practice, Virginia Tech, Blacksburg, Virginia 24061.
Vet Clin Pathol. 1983;12(2):9-24. doi: 10.1111/j.1939-165x.1983.tb00609.x.
Changes in plasma or serum enzymes and isoenzymes are useful indicators of tissue damage in many diseases. Enzyme increases are usually related to leakage of enzymes from damaged cells. The amount of increase depends on factors such as the concentration of enzyme in the cells, the rate of leakage of enzyme from cells and the rate of clearance of enzyme from plasma. There are important species variations in the tissue concentrations and plasma clearance rates of enzymes and isoenzymes.
血浆或血清酶及同工酶的变化是许多疾病中组织损伤的有用指标。酶升高通常与酶从受损细胞泄漏有关。升高的程度取决于细胞内酶的浓度、酶从细胞泄漏的速率以及酶从血浆中清除的速率等因素。酶及同工酶的组织浓度和血浆清除率存在重要的物种差异。
