Masci Giovanna, Magagnoli Massimo, Grimaldi Andrea, Covini Giovanni, Carnaghi Carlo, Rimassa Lorenza, Santoro Armando
Department of Medical Oncology and Hematology, Istituto Clinico Humanitas, Rozzano, Milan, Italy.
Tumori. 2004 May-Jun;90(3):345-7. doi: 10.1177/030089160409000317.
Hepatocellular carcinoma (HCC) with extension or metastasis to the right atrium is an uncommon form of cardiac malignancy. This report describes a rare case of right intraventricular metastasis from HCC in a patient who had undergone a partial hepatectomy for HCC more than two years earlier. Open heart surgery was performed and the mass was partially excised. Symptoms (dyspnea, edema of the lower extremities, palpitations) improved after surgery. Two months later a recurrence of the ventricular mass was observed. Systemic chemotherapy with cisplatin and doxorubicin resulted in significant tumor reduction. The patient died of progressive hepatic failure six months later. In addition to this case report, a review of the literature on heart involvement from HCC is presented.
肝细胞癌（HCC）侵犯或转移至右心房是一种罕见的心脏恶性肿瘤形式。本报告描述了1例罕见的HCC右心室内转移病例，该患者在两年多前因HCC接受了部分肝切除术。患者接受了心脏直视手术，肿块被部分切除。术后症状（呼吸困难、下肢水肿、心悸）有所改善。两个月后，观察到心室肿块复发。顺铂和阿霉素全身化疗使肿瘤显著缩小。6个月后，患者死于进行性肝衰竭。除了本病例报告外，还对HCC累及心脏的文献进行了综述。
