Briem D, Windolf J, Lehmann W, Begemann P G C, Meenen N M, Rueger J M, Linhart W
Klinik und Poliklinik für Unfall-, Hand und Wiederherstellungschirurgie, Zentrum für Operative Medizin, Universitätsklinikum, Hamburg-Eppendorf.
Unfallchirurg. 2004 Dec;107(12):1152-61. doi: 10.1007/s00113-004-0822-y.
The application of autogenous bone grafts represents the golden standard for reconstruction of the load-bearing anterior column in the thoracolumbar spine. However, the osseous integration of the implanted grafts is demanding and delayed union or pseudarthrosis may occur. There are no standardized data available yet indicating the further course in such cases. The aim of this study was to evaluate the incorporation of endoscopically applied grafts and to develop therapeutic strategies for delayed or non-fusions. Twenty patients suffering from unstable injuries of the thoracolumbar spine were studied in a prospective clinical trial. After primary dorsal stabilization, the anterior column was thoracoscopically reconstructed with an autogenous iliac crest graft and a fixed-angle implant (MACS). The osseous integration of the bone grafts was detected by MSCT 1 year postoperatively. Complete integration of the transplanted bone grafts was observed in only 65% of the cases. In 25% partial integration was detected and in two cases a fracture of the transplanted iliac crest graft occurred. Despite the incomplete integration of the bone grafts, the further course without surgical intervention revealed no clinical or radiological evidence of a concomitant implant loosening or a relevant secondary loss of correction. Similar to the open technique, endoscopic reconstruction of the anterior column with autogenous bone grafts may lead to disadvantageous results concerning the integration and healing of the applied bone grafts. Decision making in such cases depends on the individual clinical and radiological findings (i.e., evidence of implant loosening and concomitant loss of correction).
自体骨移植的应用是胸腰椎承重前柱重建的金标准。然而,植入骨移植的骨整合要求较高,可能会出现延迟愈合或假关节形成。目前尚无标准化数据表明此类情况下的后续病程。本研究的目的是评估内镜应用骨移植的融合情况,并制定针对延迟融合或不融合的治疗策略。在一项前瞻性临床试验中对20例胸腰椎不稳定损伤患者进行了研究。在进行初次后路稳定后,通过胸腔镜用自体髂嵴骨移植和固定角度植入物(MACS)对前柱进行重建。术后1年通过MSCT检测骨移植的骨整合情况。仅65%的病例观察到移植骨完全融合。25%的病例检测到部分融合,2例发生了移植髂嵴骨骨折。尽管骨移植未完全融合,但未经手术干预的后续病程未显示伴随植入物松动或相关继发矫正丢失的临床或影像学证据。与开放技术类似,自体骨移植内镜重建前柱在应用骨移植的融合和愈合方面可能会导致不利结果。此类情况下的决策取决于个体的临床和影像学表现(即植入物松动和伴随矫正丢失的证据)。