Shipton Deborah, Glazier Richard H, Guan Jun, Badley Elizabeth M
Arthritis Community Research and Evaluation Unit, Toronto Western Research Institute, University of Toronto, Toronto, Canada.
Med Care. 2004 Sep;42(9):907-13. doi: 10.1097/01.mlr.0000135810.39691.f6.
In community settings, disease-modifying antirheumatic drug (DMARD) use for rheumatoid arthritis (RA) falls short of treatment recommendations. This population-based study investigates the relationship between the use of DMARDs and specialty care in an insured population.
A cohort of individuals aged 65 or older with RA was identified from a population-based physician billing database in Ontario, Canada, together with information on visit rates to general and specialist physicians and visit-specific diagnoses. DMARD prescription data were obtained from the Ontario Drug Benefits Plan database. The proportions of individuals with RA using DMARDs and specialist care were calculated for the 43 counties in Ontario, and the relationship between the 2 was determined using logistic multilevel modeling, controlling for possible confounders.
A total of 13,698 RA individuals aged 65 or older were identified, representing 1% of the 65-or-older population. Within this cohort, 58% received DMARDs and 68% made 1 or more RA-related visits to a specialist in 3 years. There was considerable variation by county in both the proportion of those with RA making visits to specialists (39-82 per 100 RA population) and receiving DMARDs (36-81%). The use of DMARDs was significantly associated with the use of specialist services by individuals with RA (odds ratio 1.9 [95% confidence interval 1.87, 1.88] for counties with highest versus lowest proportional use of specialists) independent of effects of age, sex, income, and comorbidities.
Even in a universally funded setting, suboptimal treatment of RA is associated with lack of access to specialist services. These findings are likely applicable to many jurisdictions worldwide.
在社区环境中,类风湿关节炎(RA)患者使用改善病情抗风湿药(DMARD)的情况未达治疗建议。这项基于人群的研究调查了参保人群中DMARDs使用与专科护理之间的关系。
从加拿大安大略省基于人群的医生计费数据库中识别出一组年龄在65岁及以上的RA患者,并获取他们看全科医生和专科医生的就诊率以及特定就诊诊断信息。DMARD处方数据来自安大略省药品福利计划数据库。计算安大略省43个县中使用DMARDs和接受专科护理的RA患者比例,并使用逻辑多水平模型确定两者之间的关系,同时控制可能的混杂因素。
共识别出13,698名年龄在65岁及以上的RA患者,占65岁及以上人群的1%。在这个队列中,58%的患者接受了DMARDs治疗,68%的患者在3年内至少有1次与RA相关的专科就诊。各县在RA患者的专科就诊比例(每100名RA患者中39 - 82人次)和接受DMARDs治疗的比例(36 - 81%)方面存在很大差异。RA患者使用DMARDs与使用专科服务显著相关(专科医生使用比例最高与最低的县相比,优势比为1.9 [95%置信区间1.87, 1.88]),不受年龄、性别、收入和合并症的影响。
即使在全民医保的环境下,RA治疗不充分与难以获得专科服务有关。这些发现可能适用于世界上许多司法管辖区。