Alber M S, Kiskowski M A, Jiang Y
Mathematics Department, University of Notre Dame, Indiana 46556, USA.
Phys Rev Lett. 2004 Aug 6;93(6):068102. doi: 10.1103/PhysRevLett.93.068102. Epub 2004 Aug 4.
In response to adverse conditions, myxobacteria form aggregates that develop into fruiting bodies. We model myxobacteria aggregation with a lattice cell model based entirely on short-range (nonchemotactic) cell-cell interactions. Local rules result in a two-stage process of aggregation mediated by transient streams. Aggregates resemble those observed in experiment and are stable against even very large perturbations. Noise in individual cell behavior increases the effects of streams and results in larger, more stable aggregates.
作为对不利条件的响应,黏细菌会形成聚集体,这些聚集体进而发育成果实体。我们使用一个完全基于短程(非趋化性)细胞间相互作用的晶格细胞模型来模拟黏细菌的聚集过程。局部规则导致了一个由瞬态流介导的两阶段聚集过程。聚集体与实验中观察到的聚集体相似,并且即使面对非常大的扰动也很稳定。单个细胞行为中的噪声增加了流的影响,并导致形成更大、更稳定的聚集体。