Lehane Michael J, Aksoy Serap, Levashina Elena
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
Trends Parasitol. 2004 Sep;20(9):433-9. doi: 10.1016/j.pt.2004.07.002.
The detailed model of insect immunity being built for Drosophila, allied to mass sequencing programs for blood-feeding insects, has led to advances in our understanding of the interaction between pathogens and insect vectors. An outline of insect immunity is given here based on the Drosophila studies, which is used as a framework to discuss recent work on Plasmodium-mosquito and Trypanosoma-tsetse interactions.
正在为果蝇构建的详细昆虫免疫模型，与吸血昆虫的大规模测序计划相结合，推动了我们对病原体与昆虫载体之间相互作用的理解取得进展。本文基于果蝇研究给出了昆虫免疫的概述，以此作为框架来讨论近期关于疟原虫与蚊子以及锥虫与采采蝇相互作用的研究工作。
