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临界剂量测定的国际比对:生物剂量测定的案例

International intercomparison for criticality dosimetry: the case of biological dosimetry.

作者信息

Roy L, Buard V, Delbos M, Durand V, Paillole N, Grégoire E, Voisin P

机构信息

Institut de Radioprotection et de Sûreté Nucléaire, Direction de la radioprotection de l'homme, IRSN, BP 17 92262 Fontenay-aux roses, France.

出版信息

Radiat Prot Dosimetry. 2004;110(1-4):471-6. doi: 10.1093/rpd/nch349.

Abstract

The Institute of Radiation Protection and Nuclear Safety (IRSN) organized a biological dosimetry international intercomparison with the purpose of comparing (i) dicentrics yield produced in human lymphocytes; (ii) the gamma and neutron dose estimate according to the corresponding laboratory calibration curve. The experimental reactor SILENE was used with different configurations: bare source 4 Gy, lead shield 1 and 2 Gy and a 60Co source 2 Gy. An increasing variation of dicentric yield per cell was observed between participants when there were more damages in the samples. Doses were derived from the observed dicentric rates according to the dose-effect relationship provided by each laboratory. Differences in dicentric rate values are more important than those in the corresponding dose values. The doses obtained by the participants were found to be in agreement with the given physical dose within 20%. The evaluation of the respective gamma and neutron dose was achieved only by four laboratories, with some small variations among them.

摘要

辐射防护与核安全研究所(IRSN)组织了一次生物剂量学国际比对,目的是比较:(i)人淋巴细胞中产生的双着丝粒体产额;(ii)根据相应实验室校准曲线得出的γ射线和中子剂量估计值。实验反应堆SILENE采用了不同配置:裸源4 Gy、铅屏蔽1 Gy和2 Gy以及60Co源2 Gy。当样本中的损伤更多时,参与者之间观察到每个细胞双着丝粒体产额的变化增加。根据每个实验室提供的剂量效应关系,从观察到的双着丝粒体率得出剂量。双着丝粒体率值差异比相应剂量值差异更显著。发现参与者获得的剂量与给定物理剂量的偏差在20%以内。只有四个实验室完成了各自γ射线和中子剂量的评估,它们之间存在一些小差异。

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