Scotti A L, Nitsch C
Anatomisches Institut Universität Basel, Switzerland.
Anat Embryol (Berl). 1992;185(2):163-7. doi: 10.1007/BF00185917.
The distribution of the Ca(2+)-binding proteins parvalbumin (PV) and calbindin D-28k (CaBP) was investigated in the human cerebellar cortex. Purkinje cells contain both PV and CaBP. PV but not CaBP stains stellate and basket cells in the molecular layer. In the granular layer Golgi neurons can be subdivided into a majority, devoid of both Ca(2+)-binding proteins, and a scanty population which appears to be PV- and CaBP-immunoreactive. Thus GABAergic neurons in the human cerebellar cortex show selective differences in their Ca(2+)-binding properties, and these differences might reflect a heterogeneity in the processing of Ca(2+)-mediated events.
研究了人小脑皮质中钙结合蛋白小白蛋白（PV）和钙结合蛋白D-28k（CaBP）的分布。浦肯野细胞同时含有PV和CaBP。PV而非CaBP可使分子层中的星状细胞和篮状细胞染色。在颗粒层，高尔基神经元可分为大多数不含这两种钙结合蛋白的神经元，以及少量似乎对PV和CaBP呈免疫反应性的神经元。因此，人小脑皮质中的γ-氨基丁酸能神经元在其钙结合特性上表现出选择性差异，这些差异可能反映了钙介导事件处理过程中的异质性。
