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Formation of nucleoside 5'-phosphoramidates under potentially prebiological conditions.

作者信息

Lohrmann R

出版信息

J Mol Evol. 1977 Nov 25;10(2):137-54. doi: 10.1007/BF01751807.

DOI:10.1007/BF01751807
PMID:592420
Abstract

Adenosine 5'-phosphoramidates form when solutions containing adenosine 5'-polyphosphates pnA (n greater than or equal to 3) or P1, P2-diadenosine 5'-diphosphate and amines are allowed to dry out. Mg ions catalyze these reactions. We have studied systems containing ammonia, imidazole, glycine, ethylenediamine and histamine. The yields of adenosine 5'-phosphoramidates range from 10-50% based on the nucleotide. The prebiotic significance of the reactions is discussed.

摘要

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