Wood Evan, Kerr Thomas, Small Will, Li Kathy, Marsh David C, Montaner Julio S G, Tyndall Mark W
Department of Health Care and Epidemiology, British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC.
CMAJ. 2004 Sep 28;171(7):731-4. doi: 10.1503/cmaj.1040774.
North America's first medically supervised safer injecting facility for illicit injection drug users was opened in Vancouver on Sept. 22, 2003. Although similar facilities exist in a number of European cities and in Sydney, Australia, no standardized evaluations of their impact have been presented in the scientific literature.
Using a standardized prospective data collection protocol, we measured injection-related public order problems during the 6 weeks before and the 12 weeks after the opening of the safer injecting facility in Vancouver. We measured changes in the number of drug users injecting in public, publicly discarded syringes and injection-related litter. We used Poisson log-linear regression models to evaluate changes in these public order indicators while considering potential confounding variables such as police presence and rainfall.
In stratified linear regression models, the 12-week period after the facility's opening was independently associated with reductions in the number of drug users injecting in public (p < 0.001), publicly discarded syringes (p < 0.001) and injection-related litter (p < 0.001). The predicted mean daily number of drug users injecting in public was 4.3 (95% confidence interval [CI] 3.5-5.4) during the period before the facility's opening and 2.4 (95% CI 1.9-3.0) after the opening; the corresponding predicted mean daily numbers of publicly discarded syringes were 11.5 (95% CI 10.0-13.2) and 5.4 (95% CI 4.7-6.2). Externally compiled statistics from the city of Vancouver on the number of syringes discarded in outdoor safe disposal boxes were consistent with our findings.
The opening of the safer injecting facility was independently associated with improvements in several measures of public order, including reduced public injection drug use and public syringe disposal.
2003年9月22日,北美首个为非法注射吸毒者设立的有医学监督的更安全注射场所在温哥华开业。尽管在一些欧洲城市和澳大利亚悉尼也有类似场所,但科学文献中尚未出现对其影响的标准化评估。
我们采用标准化的前瞻性数据收集方案,在温哥华更安全注射场所开业前6周和开业后12周测量与注射相关的公共秩序问题。我们测量了在公共场所注射毒品的使用者数量、公共场合丢弃的注射器及与注射相关的垃圾的变化情况。我们使用泊松对数线性回归模型来评估这些公共秩序指标的变化,同时考虑潜在的混杂变量,如警察在场情况和降雨量。
在分层线性回归模型中,场所开业后的12周与公共场所注射毒品的使用者数量减少(p<0.001)、公共场合丢弃的注射器数量减少(p<0.001)以及与注射相关的垃圾数量减少(p<0.001)独立相关。场所开业前,预测的每日在公共场所注射毒品的使用者平均数量为4.3(95%置信区间[CI]3.5 - 5.4),开业后为2.4(95%CI 1.9 - 3.0);相应地,预测的每日公共场合丢弃的注射器平均数量分别为11.5(95%CI 10.0 - 13.2)和5.4(95%CI 4.7 - 6.2)。温哥华市关于户外安全处置箱中丢弃注射器数量的外部汇编统计数据与我们的研究结果一致。
更安全注射场所的开业与多项公共秩序指标的改善独立相关,包括减少公共场所注射吸毒和公共注射器处置情况。