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多枝单睾线虫:一种慢性胃肠蠕虫病的模型

Heligmosomoides polygyrus: a model for chronic gastrointestinal helminthiasis.

作者信息

Monroy F G, Enriquez F J

机构信息

Biology Department, University of New Mexico, Albuquerque, NM 87131, USA.

出版信息

Parasitol Today. 1992 Feb;8(2):49-54. doi: 10.1016/0169-4758(92)90084-f.

DOI:10.1016/0169-4758(92)90084-f
PMID:15463566
Abstract

Establishment of chronic infections and strain-dependent variation in resistance to challenge infections are well-known features of the relationship between mice and the intestinal nematode parasite Heligmosomoides polygyrus. Here, Fernando Monroy and Javier Enriquez examine host responses, immunogenic and nonimmunogenic antigens of the parasite, and parasite immune evasion strategies in this useful laboratory mouse model of nematode parasitism of mammals.

摘要

建立慢性感染以及对激发感染的抗性存在品系依赖性差异,这些都是小鼠与肠道线虫寄生虫多房棘球绦虫之间关系的已知特征。在此,费尔南多·蒙罗伊和哈维尔·恩里克斯在这个用于研究哺乳动物线虫寄生的实用实验室小鼠模型中,研究了宿主反应、寄生虫的免疫原性和非免疫原性抗原,以及寄生虫的免疫逃避策略。

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