Elliot William J, Izzo Joseph L, White William B, Rosing Douglas R, Snyder Christopher S, Alter Ariela, Gavish Benjamin, Black Henry R
Department of Preventive Medicine, RUSH Medical College of RUSH University, RUSH University Medical Center, Chicago, IL 60612, USA.
J Clin Hypertens (Greenwich). 2004 Oct;6(10):553-9; quiz 560-1. doi: 10.1111/j.1524-6175.2004.03553.x.
To study the effects of device-guided breathing on office systolic blood pressure (SBP), five centers randomized 149 untrained hypertensives (50% male, age 59+/-10 years, baseline blood pressure 150+/-9/86+/-9 mm Hg, 77% taking drug therapy). One half received a device to guide slow breathing; all received a home blood pressure monitor and only simple, written instructions. The changes in office SBP (adjusted for office-to-home difference in baseline SBP and accumulated time spent in slow breathing, guided and measured by the device) were significantly (p<0.001 for trend) correlated with accumulated time spent in slow breathing. Greater decreases in SBP (-15.0+/-1.8 vs. -7.3+/-1.9 mm Hg) were observed for those who spent more (vs. less) than 180 minutes over 8 weeks in slow breathing, as well as those who just monitored their blood pressure at home (-9.2+/-1.6 mm Hg). Thus, even without training, hypertensive patients who receive a device to guide slow breathing significantly lowered their office SBP if the total time spent in slow breathing over 8 weeks exceeded a "threshold" value of 180 minutes.
为研究设备引导呼吸对诊室收缩压（SBP）的影响，五个中心对149名未经训练的高血压患者进行了随机分组（50%为男性，年龄59±10岁，基线血压150±9/86±9 mmHg，77%正在接受药物治疗）。其中一半患者获得了引导慢呼吸的设备；所有患者均获得了家用血压监测仪且仅收到简单的书面说明。诊室SBP的变化（根据基线SBP的诊室与家庭差异以及设备引导和测量的慢呼吸累计时间进行调整）与慢呼吸累计时间显著相关（趋势p<0.001）。在8周内慢呼吸时间超过180分钟的患者（与慢呼吸时间较短的患者相比）以及仅在家中监测血压的患者，SBP下降幅度更大（分别为-15.0±1.8 vs. -7.3±1.9 mmHg和-9.2±1.6 mmHg）。因此，即使未经训练，若8周内慢呼吸的总时间超过180分钟这一“阈值”，接受引导慢呼吸设备的高血压患者的诊室SBP会显著降低。
