Collins Linda M, Murphy Susan A, Bierman Karen L
The Methodology Center and Department of Human Development and Family Studies, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Prev Sci. 2004 Sep;5(3):185-96. doi: 10.1023/b:prev.0000037641.26017.00.
Recently, adaptive interventions have emerged as a new perspective on prevention and treatment. Adaptive interventions resemble clinical practice in that different dosages of certain prevention or treatment components are assigned to different individuals, and/or within individuals across time, with dosage varying in response to the intervention needs of individuals. To determine intervention need and thus assign dosage, adaptive interventions use prespecified decision rules based on each participant's values on key characteristics, called tailoring variables. In this paper, we offer a conceptual framework for adaptive interventions, discuss principles underlying the design and evaluation of such interventions, and review some areas where additional research is needed.
最近，适应性干预已成为预防和治疗的一种新视角。适应性干预类似于临床实践，即某些预防或治疗成分的不同剂量被分配给不同个体，和/或在个体内随时间变化，剂量根据个体的干预需求而变化。为了确定干预需求并因此分配剂量，适应性干预使用基于每个参与者在关键特征（称为定制变量）上的值的预先指定的决策规则。在本文中，我们提供了一个适应性干预的概念框架，讨论了此类干预设计和评估的基本原则，并回顾了一些需要进一步研究的领域。
