Macé Muriel, Cointe Denis, Six Caroline, Levy-Bruhl Daniel, Parent du Châtelet Isabelle, Ingrand Didier, Grangeot-Keros Liliane
Service de Microbiologie-Immunologie biologique, Hôpital Antoine Béclère, Clamart, France.
J Clin Microbiol. 2004 Oct;42(10):4818-20. doi: 10.1128/JCM.42.10.4818-4820.2004.
The diagnostic value of RT-PCR of amniotic fluid (AF) for prenatal diagnosis of congenital rubella virus infection in 45 pregnant women with confirmed primary infection was assessed. Specificity of RT-PCR was 100% and sensitivity ranged between 83 and 95%.
评估了45例确诊为原发性感染的孕妇羊水逆转录聚合酶链反应(RT-PCR)对先天性风疹病毒感染产前诊断的价值。RT-PCR的特异性为100%,敏感性在83%至95%之间。