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羊水逆转录聚合酶链反应对确诊原发性风疹感染孕妇先天性风疹感染产前诊断的价值

Diagnostic value of reverse transcription-PCR of amniotic fluid for prenatal diagnosis of congenital rubella infection in pregnant women with confirmed primary rubella infection.

作者信息

Macé Muriel, Cointe Denis, Six Caroline, Levy-Bruhl Daniel, Parent du Châtelet Isabelle, Ingrand Didier, Grangeot-Keros Liliane

机构信息

Service de Microbiologie-Immunologie biologique, Hôpital Antoine Béclère, Clamart, France.

出版信息

J Clin Microbiol. 2004 Oct;42(10):4818-20. doi: 10.1128/JCM.42.10.4818-4820.2004.

Abstract

The diagnostic value of RT-PCR of amniotic fluid (AF) for prenatal diagnosis of congenital rubella virus infection in 45 pregnant women with confirmed primary infection was assessed. Specificity of RT-PCR was 100% and sensitivity ranged between 83 and 95%.

摘要

评估了45例确诊为原发性感染的孕妇羊水逆转录聚合酶链反应(RT-PCR)对先天性风疹病毒感染产前诊断的价值。RT-PCR的特异性为100%,敏感性在83%至95%之间。

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