Liebana Ernesto, Batchelor Miranda, Torres Carmen, Briñas Laura, Lagos Luis A, Abdalhamid Baha, Hanson Nancy D, Martinez-Urtaza Jaime
Instituto de Acuicultura, Universidad de Santiago de Compostela, Spain.
J Clin Microbiol. 2004 Oct;42(10):4885-8. doi: 10.1128/JCM.42.10.4885-4888.2004.
We report the case of a pediatric patient with a Salmonella enterica serotype Infantis infection. Detailed microbiological investigation revealed that this isolate carries four beta-lactamase genes (bla(TEM-1b) variant, bla(SHV-5), bla(CTX-M-15), and bla(CMY-2)) conferring resistance to all beta-lactams but imipenem. This is the first report of a Salmonella isolate with CTX-M and AmpC enzymes on the American continent, the first report of bla(CMY-2) in Salmonella serotype Infantis, and the first report of bla(CTX-M-15) in the genus Salmonella.
我们报告了一例患有肠炎沙门氏菌婴儿亚种感染的儿科患者病例。详细的微生物学调查显示，该分离株携带四种β-内酰胺酶基因（bla(TEM-1b)变体、bla(SHV-5)、bla(CTX-M-15)和bla(CMY-2)），对除亚胺培南外的所有β-内酰胺类药物均具有耐药性。这是美洲大陆首次报告带有CTX-M和AmpC酶的沙门氏菌分离株，首次报告肠炎沙门氏菌婴儿亚种中存在bla(CMY-2)，以及首次报告沙门氏菌属中存在bla(CTX-M-15)。
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