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The stroke-prone spontaneously hypertensive rat: how good is it as a model for cerebrovascular diseases?
Cell Mol Neurobiol. 2004 Oct;24(5):639-46. doi: 10.1023/b:cemn.0000036402.79129.2f.
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Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats.
Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2455-65. doi: 10.1152/ajpheart.00512.2008. Epub 2008 Oct 24.
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Plasma Kallikrein Contributes to Intracerebral Hemorrhage and Hypertension in Stroke-Prone Spontaneously Hypertensive Rats.
Transl Stroke Res. 2022 Apr;13(2):287-299. doi: 10.1007/s12975-021-00929-x. Epub 2021 Jul 9.
7
Urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat and stroke-prone spontaneously hypertensive rat.
Clin Exp Pharmacol Physiol Suppl. 1995 Dec;22(1):S20-2. doi: 10.1111/j.1440-1681.1995.tb02882.x.
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Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat.
Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1489-94. doi: 10.1152/ajpheart.00352.2003. Epub 2003 Jun 19.

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Urinary Proteome Characterization of Stroke-Prone Spontaneously Hypertensive Rats.
Int J Mol Sci. 2024 Dec 24;26(1):21. doi: 10.3390/ijms26010021.
2
Endothelial Nitric Oxide Synthase-Deficient Mice: A Model of Spontaneous Cerebral Small-Vessel Disease.
Am J Pathol. 2021 Nov;191(11):1932-1945. doi: 10.1016/j.ajpath.2021.02.022. Epub 2021 Mar 10.
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Mycophenolate mofetil prevents cerebrovascular injury in stroke-prone spontaneously hypertensive rats.
Physiol Genomics. 2017 Mar 1;49(3):132-140. doi: 10.1152/physiolgenomics.00110.2016. Epub 2016 Dec 23.
8
Impact of Comorbidities on Acute Injury and Recovery in Preclinical Stroke Research: Focus on Hypertension and Diabetes.
Transl Stroke Res. 2016 Aug;7(4):248-60. doi: 10.1007/s12975-016-0464-8. Epub 2016 Mar 30.
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Spontaneous white matter lesion in brain of stroke-prone renovascular hypertensive rats: a study from MRI, pathology and behavior.
Metab Brain Dis. 2015 Dec;30(6):1479-86. doi: 10.1007/s11011-015-9722-9. Epub 2015 Sep 19.

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Nitric oxide deficiency contributes to large cerebral infarct size.
Hypertension. 2000 May;35(5):1111-8. doi: 10.1161/01.hyp.35.5.1111.
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Impaired blood-brain barrier function in angiotensinogen-deficient mice.
Nat Med. 1998 Sep;4(9):1078-80. doi: 10.1038/2070.
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Two-kidney, two clip renovascular hypertensive rats can be used as stroke-prone rats.
Stroke. 1998 Aug;29(8):1708-13; discussion 1713-4. doi: 10.1161/01.str.29.8.1708.
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The region responsible for stroke on chromosome 4 in the stroke-prone spontaneously hypertensive rat.
Biochem Biophys Res Commun. 1996 Dec 13;229(2):658-62. doi: 10.1006/bbrc.1996.1860.

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