Bergfeld Wilma F
Department of Dermatology, Cleveland Clinic Foundation, Ohio 44195, USA.
Cutis. 2004 Sep;74(3):189-92.
Various pathophysiologic factors are involved in the development of acne lesions, microcomedones, comedones, and inflammatory lesions. These factors include follicular hyperkeratosis, increased colonization of follicles by Propionibacterium acnes, increased sebum production, and inflammatory mediators. Optimal treatment of acne involves the use of agents that address these various underlying pathogenetic factors.
多种病理生理因素参与痤疮皮损、微粉刺、粉刺和炎性皮损的形成。这些因素包括毛囊过度角化、痤疮丙酸杆菌在毛囊中的定植增加、皮脂分泌增加以及炎症介质。痤疮的最佳治疗方法是使用能够解决这些各种潜在致病因素的药物。
