Marrugat Jaume, Elosua Roberto, Aldasoro Elena, Tormo María José, Vanaclocha Hermelinda, Segura Antonio, Fiol Miquel, Moreno-Iribas Concepción, Pérez Gloria, Arteagoitia José María, Cirera Lluis, Cabadés Adolfo, Vega Gema, Ayestarán José Ignacio, García Vega, Hurtado-de-Saracho Iraida, García José, Zurriaga Oscar, Muñiz Javier, Sala Joan
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d'Investigació Medica, Barcelona, Spain.
Eur J Epidemiol. 2004;19(9):831-9. doi: 10.1023/b:ejep.0000040531.77638.17.
Myocardial infarction (MI) incidence and mortality display a high geographic variation.
The objective of the present study was to analyze MI mortality, cumulative incidence rate variability in seven regions of Spain from 1997 to 1998.
Standardized methods were used to identify, find, register, and classify MI cases that were classified as definite, possible, insufficient-data MI, and non-MI. The total population of the seven monitored regions was 7,364,682 inhabitants. Of the 11,256 cases fulfilling eligibility criteria to investigate, 10,660 were selected to calculate MI rates: 6554 (61.5%) non-fatal definite MI, 1179 (11.1%) fatal definite MI, 1859 (17.4%) fatal possible MI, 1068 (10.0%) fatal cases with insufficient data. The IBERICA 25-74 years age-standardized cumulative incidence rates for men and women, were 207 (range: 175-252) and 45 (range: 36-65) per 100,000, respectively. The age-standardized mortality rates for men and women, were 73 (range: 62-94) and 20 (range: 13-29) per 100,000, respectively. Age-standardized case-fatality was 31.4 and 24.2% in men aged 25-74 and 35-64 years, respectively, and 32.7 and 27.0%, respectively, in women.
MI cumulative incidence and mortality rates are low compared with other industrialized countries but, vary considerably among regions in a Mediterranean country like Spain.
心肌梗死（MI）的发病率和死亡率存在很大的地域差异。
本研究的目的是分析1997年至1998年西班牙七个地区的MI死亡率、累积发病率的变异性。
采用标准化方法识别、查找、登记和分类MI病例，这些病例被分类为确诊、可能、数据不足的MI和非MI。七个监测地区的总人口为7364682名居民。在符合调查资格标准的11256例病例中，选择了10660例来计算MI发病率：6554例（61.5%）非致命确诊MI，1179例（11.1%）致命确诊MI，1859例（17.4%）致命可能MI，1068例（10.0%）数据不足的致命病例。男性和女性的IBERICA 25 - 74岁年龄标准化累积发病率分别为每10万人207例（范围：175 - 252）和45例（范围：36 - 65）。男性和女性的年龄标准化死亡率分别为每10万人73例（范围：62 - 94）和20例（范围：13 - 29）。25 - 74岁男性和35 - 64岁女性的年龄标准化病死率分别为31.4%和24.2%，女性分别为32.7%和27.0%。
与其他工业化国家相比，MI的累积发病率和死亡率较低，但在西班牙这样的地中海国家，不同地区之间存在很大差异。
