• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

利用转录序列的选择性捕获技术鉴定猪胸膜肺炎放线杆菌在坏死猪肺组织中转录的基因。

Identification of genes transcribed by Actinobacillus pleuropneumoniae in necrotic porcine lung tissue by using selective capture of transcribed sequences.

作者信息

Baltes Nina, Gerlach Gerald F

机构信息

Department of Infectious Diseases, Institute for Microbiology, University of Veterinary Medicine Hannover, Germany.

出版信息

Infect Immun. 2004 Nov;72(11):6711-6. doi: 10.1128/IAI.72.11.6711-6716.2004.

DOI:10.1128/IAI.72.11.6711-6716.2004
PMID:15501809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC523062/
Abstract

Genes expressed by Actinobacillus pleuropneumoniae in necrotic porcine lung tissue were identified by selective capture of transcribed sequences analysis. In total, 46 genes were identified, 20 of which have been previously reported to be associated with in vivo expression or virulence in A. pleuropneumoniae or in other organisms.

摘要

通过转录序列分析的选择性捕获，鉴定了胸膜肺炎放线杆菌在坏死猪肺组织中表达的基因。总共鉴定出46个基因，其中20个基因先前已报道与胸膜肺炎放线杆菌或其他生物体中的体内表达或毒力相关。

相似文献

1
Identification of genes transcribed by Actinobacillus pleuropneumoniae in necrotic porcine lung tissue by using selective capture of transcribed sequences.利用转录序列的选择性捕获技术鉴定猪胸膜肺炎放线杆菌在坏死猪肺组织中转录的基因。
Infect Immun. 2004 Nov;72(11):6711-6. doi: 10.1128/IAI.72.11.6711-6716.2004.
2
Selective capture of transcribed sequences (SCOTS) of Actinobacillus pleuropneumoniae in the chronic stage of disease reveals an HlyX-regulated autotransporter protein.胸膜肺炎放线杆菌疾病慢性期转录序列的选择性捕获（SCOTS）揭示了一种HlyX调控的自转运蛋白。
Vet Microbiol. 2007 Jul 20;123(1-3):110-21. doi: 10.1016/j.vetmic.2007.03.026. Epub 2007 Mar 30.
3
Differential expression of non-cytoplasmic Actinobacillus pleuropneumoniae proteins induced by addition of bronchoalveolar lavage fluid.添加支气管肺泡灌洗液诱导的胸膜肺炎放线杆菌非细胞质蛋白的差异表达
Vet Microbiol. 2005 Aug 30;109(3-4):245-56. doi: 10.1016/j.vetmic.2005.05.013.
4
An isogenic Actinobacillus pleuropneumoniae AasP mutant exhibits altered biofilm formation but retains virulence.一株胸膜肺炎放线杆菌AasP同基因缺失突变株表现出生物膜形成改变，但仍保留毒力。
Vet Microbiol. 2009 Jun 12;137(3-4):392-6. doi: 10.1016/j.vetmic.2009.01.026. Epub 2009 Jan 24.
5
Identification of in vivo induced genes in Actinobacillus pleuropneumoniae.猪胸膜肺炎放线杆菌体内诱导基因的鉴定
Microb Pathog. 1999 Nov;27(5):311-27. doi: 10.1006/mpat.1999.0309.
6
Concurrent host-pathogen gene expression in the lungs of pigs challenged with Actinobacillus pleuropneumoniae.用胸膜肺炎放线杆菌攻毒的猪肺中宿主与病原体的基因共表达
BMC Genomics. 2015 May 28;16(1):417. doi: 10.1186/s12864-015-1557-6.
7
Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model.在猪感染模型中使用签名标签诱变技术鉴定胸膜肺炎放线杆菌毒力基因。
Microb Pathog. 2000 Jul;29(1):39-51. doi: 10.1006/mpat.2000.0364.
8
Differential gene expression profiling of Actinobacillus pleuropneumoniae during induction of primary alveolar macrophage apoptosis in piglets.猪肺炎放线杆菌诱导仔猪原代肺泡巨噬细胞凋亡过程中的差异基因表达谱分析
Microb Pathog. 2015 Jan;78:74-86. doi: 10.1016/j.micpath.2014.11.017. Epub 2014 Nov 28.
9
In vivo induced RTX toxin ApxIVA is essential for the full virulence of Actinobacillus pleuropneumoniae.体内诱导的RTX毒素ApxIVA对于胸膜肺炎放线杆菌的完全毒力至关重要。
Vet Microbiol. 2009 Jun 12;137(3-4):282-9. doi: 10.1016/j.vetmic.2009.01.011. Epub 2009 Jan 8.
10
Mutation in the LPS outer core biosynthesis gene, galU, affects LPS interaction with the RTX toxins ApxI and ApxII and cytolytic activity of Actinobacillus pleuropneumoniae serotype 1.脂多糖（LPS）外核心生物合成基因galU的突变影响LPS与RTX毒素ApxI和ApxII的相互作用以及胸膜肺炎放线杆菌1型的细胞溶解活性。
Mol Microbiol. 2008 Oct;70(1):221-35. doi: 10.1111/j.1365-2958.2008.06409.x. Epub 2008 Aug 18.

引用本文的文献

1
Sludge amended soil induced multidrug and heavy metal resistance in endophytic Exiguobacterium sp. E21L: genomics evidences.污泥改良土壤诱导内生短小杆菌属E21L产生多重耐药性和重金属抗性：基因组学证据
World J Microbiol Biotechnol. 2025 Mar 28;41(4):114. doi: 10.1007/s11274-025-04323-9.
2
Surviving on Environmental Multi-Species Biofilms in Swine Farms.在养猪场的环境多物种生物膜上生存。
Front Vet Sci. 2021 Sep 30;8:722683. doi: 10.3389/fvets.2021.722683. eCollection 2021.
3
Insights into Campylobacter jejuni colonization and enteritis using a novel infant rabbit model.利用新型婴儿兔模型深入研究空肠弯曲菌定植和肠炎。
Sci Rep. 2016 Jun 30;6:28737. doi: 10.1038/srep28737.
4
Selective Capture of Transcribed Sequences: A Promising Approach for Investigating Bacterium-Insect Interactions.转录序列的选择性捕获：一种研究细菌-昆虫相互作用的有前景的方法。
Insects. 2012 Mar 2;3(1):295-306. doi: 10.3390/insects3010295.
5
Transcriptional portrait of Actinobacillus pleuropneumoniae during acute disease--potential strategies for survival and persistence in the host.急性病期间胸膜肺炎放线杆菌的转录特征——在宿主中生存和持续存在的潜在策略。
PLoS One. 2012;7(4):e35549. doi: 10.1371/journal.pone.0035549. Epub 2012 Apr 17.
6
Global effects of catecholamines on Actinobacillus pleuropneumoniae gene expression.儿茶酚胺对胸膜肺炎放线杆菌基因表达的全球影响。
PLoS One. 2012;7(2):e31121. doi: 10.1371/journal.pone.0031121. Epub 2012 Feb 8.
7
Predicting genetic traits and epitope analysis of apxIVA in Actinobacillus pleuropneumoniae.预测胸膜肺炎放线杆菌中 apxIVA 的遗传特征和表位分析。
J Microbiol. 2011 Jun;49(3):462-8. doi: 10.1007/s12275-011-0449-y. Epub 2011 Jun 30.
8
Proteomic and immunoproteomic characterization of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae.对胸膜肺炎放线杆菌 DIVA 亚单位疫苗的蛋白质组学和免疫蛋白质组学分析。
Proteome Sci. 2011 Apr 20;9(1):23. doi: 10.1186/1477-5956-9-23.
9
Methods for transcriptomic analyses of the porcine host immune response: application to Salmonella infection using microarrays.猪宿主免疫反应的转录组分析方法：使用微阵列在沙门氏菌感染中的应用。
Vet Immunol Immunopathol. 2010 Dec 15;138(4):280-91. doi: 10.1016/j.vetimm.2010.10.006. Epub 2010 Oct 14.
10
Virulence factors of Actinobacillus pleuropneumoniae involved in colonization, persistence and induction of lesions in its porcine host.胸膜肺炎放线杆菌在猪体内定植、持续存在和诱导病变涉及的毒力因子。
Vet Res. 2010 Sep-Oct;41(5):65. doi: 10.1051/vetres/2010037. Epub 2010 Jun 15.

本文引用的文献

1
Molecular cloning of haemoglobin-binding protein HgbA in the outer membrane of Actinobacillus pleuropneumoniae.
Microbiology (Reading). 2004 Jun;150(Pt 6):1723-1734. doi: 10.1099/mic.0.27046-0.
2
Haemophilus ducreyi requires an intact flp gene cluster for virulence in humans.杜克雷嗜血杆菌在人类中致病需要完整的flp基因簇。
Infect Immun. 2003 Dec;71(12):7178-82. doi: 10.1128/IAI.71.12.7178-7182.2003.
3
Identification of dimethyl sulfoxide reductase in Actinobacillus pleuropneumoniae and its role in infection.胸膜肺炎放线杆菌中二甲基亚砜还原酶的鉴定及其在感染中的作用。
Infect Immun. 2003 Dec;71(12):6784-92. doi: 10.1128/IAI.71.12.6784-6792.2003.
4
A search for virulence genes of Haemophilus parasuis using differential display RT-PCR.
Vet Microbiol. 2003 Oct 17;96(2):189-202. doi: 10.1016/s0378-1135(03)00212-8.
5
Effect of enzyme I of the bacterial phosphoenolpyruvate : sugar phosphotransferase system (PTS) on virulence in a murine model.细菌磷酸烯醇丙酮酸：糖磷酸转移酶系统（PTS）中酶I对小鼠模型中致病性的影响。
Microbiology (Reading). 2003 Sep;149(Pt 9):2645-2652. doi: 10.1099/mic.0.26406-0.
6
Regulation of dinucleoside polyphosphate pools by the YgdP and ApaH hydrolases is essential for the ability of Salmonella enterica serovar typhimurium to invade cultured mammalian cells.YgdP和ApaH水解酶对二核苷多磷酸库的调节对于鼠伤寒沙门氏菌侵袭培养的哺乳动物细胞的能力至关重要。
J Biol Chem. 2003 Aug 29;278(35):32602-7. doi: 10.1074/jbc.M305994200. Epub 2003 Jun 24.
7
Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host.鉴定胸膜肺炎放线杆菌在其自然宿主感染期间生存所必需的基因。
Infect Immun. 2003 Jul;71(7):3960-70. doi: 10.1128/IAI.71.7.3960-3970.2003.
8
Actinobacillus pleuropneumoniae serotype 7 siderophore receptor FhuA is not required for virulence.胸膜肺炎放线杆菌7型铁载体受体FhuA对毒力并非必需。
FEMS Microbiol Lett. 2003 Mar 14;220(1):41-8. doi: 10.1016/S0378-1097(03)00064-8.
9
DsbA of Pseudomonas aeruginosa is essential for multiple virulence factors.铜绿假单胞菌的DsbA对多种毒力因子至关重要。
Infect Immun. 2003 Mar;71(3):1590-5. doi: 10.1128/IAI.71.3.1590-1595.2003.
10
Application of a novel multi-screening signature-tagged mutagenesis assay for identification of Klebsiella pneumoniae genes essential in colonization and infection.一种新型多筛选标记诱变检测法在鉴定肺炎克雷伯菌定植和感染中必需基因的应用。
Microbiology (Reading). 2003 Jan;149(Pt 1):167-76. doi: 10.1099/mic.0.25833-0.