Erie J C, Nevitt M P, Hodge D, Ballard D J
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905.
Am J Ophthalmol. 1992 Feb 15;113(2):138-44. doi: 10.1016/s0002-9394(14)71525-9.
We conducted a population-based study of long-term trends in the incidence of enucleation. From 1956 through 1988, enucleation was performed on 99 residents (55 males and 44 females) of Olmsted County, Minnesota. The mean annual age-adjusted incidence per 100,000 population for males (5.17) was 50% greater than that for females (3.49; P = .04). An increase in the enucleation rate was noted with increasing age (P = .001), with the highest incidence in patients who were 70 to 79 years of age. A decrease in the incidence of enucleation over time (P = .002) was observed in Olmsted County residents who were at least 40 years of age and was caused primarily by the decreasing incidence of neovascular glaucoma and tumor-related enucleations. The incidence of traumatic enucleations did not significantly decrease (P = .25) over this three-decade study period.
我们开展了一项基于人群的眼球摘除术发病率长期趋势研究。1956年至1988年期间，明尼苏达州奥尔姆斯特德县的99名居民（55名男性和44名女性）接受了眼球摘除术。每10万人口中男性的年龄调整后年发病率均值（5.17）比女性（3.49；P = 0.04）高50%。随着年龄增长，眼球摘除率上升（P = 0.001），70至79岁患者的发病率最高。在至少40岁的奥尔姆斯特德县居民中，观察到眼球摘除术发病率随时间下降（P = 0.002），这主要是由于新生血管性青光眼和肿瘤相关眼球摘除术的发病率降低所致。在这三十年的研究期间，外伤性眼球摘除术的发病率没有显著下降（P = 0.25）。
