Pilas-Pomykalska Magdalena, Luczak Małgorzata, Czajkowski Janusz, Woźniak Piotr, Oszukowski Przemysław
Kliniki Okulistyki Instytutu Centrum Zdrowia Matki Polki w Lodzi.
Klin Oczna. 2004;106(1-2 Suppl):238-9.
The purpose of this study was to define physiological changes in intraocular pressure during pregnancy.
182 healthy pregnant women were examined cross-sectionally throughout the pregnancy. After measuring systolic and diastolic blood pressure full ophthalmological examination was performed (visual acuity, refractive error, intraocular pressure, slit lamp examination and fundus exam). All subjects were free from any systemic or ocular diseases.
Intraocular pressure significantly decreased during successive stages of pregnancy. The results are presented as means SD. In the control group mean IOP was 15.6 +/- 1.81 mmHg. During first ten weeks of pregnancy mean IOP was 15.33 +/- 1.98 mmHg, between 11-20 hbd was 14.52 +/- 2.37 mmHg, between 21-30 hbd was 13.47 +/- 2.19 mmHg, and towards the end of pregnancy (31-40 hbd) was 12.5 +/- 1.96 mmHg. The mean fall of IOP during whole pregnancy was 3.1 +/- 0.38 mmHg (p < 0.001). In these subjects pregnancy decreased IOP by 19.8%.
The study results showed a gradual, statistically significant fall of intraocular pressure during pregnancy.
本研究的目的是确定孕期眼压的生理变化。
对182名健康孕妇在整个孕期进行横断面检查。测量收缩压和舒张压后,进行全面的眼科检查(视力、屈光不正、眼压、裂隙灯检查和眼底检查)。所有受试者均无任何全身性或眼部疾病。
孕期各阶段眼压显著下降。结果以均值±标准差表示。对照组平均眼压为15.6±1.81 mmHg。妊娠前10周平均眼压为15.33±1.98 mmHg,妊娠11 - 20周时为14.52±2.37 mmHg,妊娠21 - 30周时为13.47±2.19 mmHg,妊娠末期(31 - 40周)为12.5±1.96 mmHg。整个孕期眼压平均下降3.1±0.38 mmHg(p < 0.001)。在这些受试者中,妊娠使眼压降低了19.8%。
研究结果显示孕期眼压呈逐渐下降趋势,且具有统计学意义。