Association of t(15;17) and t(8;21) in the initial phase of an acute promyelocytic leukemia.
作者信息
Charrin C, Ritouet D, Campos L, Devaux Y, Archimbaud E, Fraisse J, Fiere D, Germain D
机构信息
Laboratoire d'Hématologie et Cytogénétique, Hôpital Edouard Herriot, Lyon, France.
出版信息
Cancer Genet Cytogenet. 1992 Feb;58(2):177-80. doi: 10.1016/0165-4608(92)90108-k.
PMID:1551085
Abstract
Two clones were observed at the initial phase of an acute myelogenous leukemia (AML): 46,XX,t(15;17) and 46,XX,t(8;21),t(15;17). Clinical, immunologic, and morphologic findings were in favor of expression of both chromosomal anomalies. Relapse occurred after 12 months of complete remission with typical acute promyelocytic leukemia (APL) syndrome when t(15;17) alone was then most predominant.
摘要
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