1例急性早幼粒细胞白血病中两种FAB特异性染色体改变t(15;17)和t(8;21)的共表达。
Co-expression of two FAB-specific chromosome changes, t(15;17) and t(8;21), in a case of acute promyelocytic leukemia.
作者信息
Movafagh A, Varma N, Varma S
机构信息
Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Ann Hematol. 1996 Jun;72(6):375-7. doi: 10.1007/s002770050189.
PMID:8767107
Abstract
We describe a case of acute promyelocytic leukemia ANLL-M3 with association of t(15;17) and t(8;21) and various chromosomal aberrations. Clinically, immunologically, and morphologically, our patient fits the diagnosis of typical ANLL-M3. The co-existence of two specific FAB chromosomal translocations in a single leukemic clone is rare. The rarity of this association enhances the significance of this report.
摘要
我们描述了一例急性早幼粒细胞白血病ANLL-M3，伴有t(15;17)和t(8;21)以及各种染色体畸变。在临床、免疫和形态学方面，我们的患者符合典型ANLL-M3的诊断。单个白血病克隆中两种特定的FAB染色体易位共存的情况很罕见。这种关联的罕见性增强了本报告的重要性。
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