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约旦唇腭裂的出生患病率

Cleft lip and palate in Jordan: birth prevalence rate.

作者信息

Al Omari F, Al-Omari I K

机构信息

Royal Medical Services, Amman, Jordan.

出版信息

Cleft Palate Craniofac J. 2004 Nov;41(6):609-12. doi: 10.1597/03-034.1.

Abstract

OBJECTIVE AND DESIGN

A retrospective investigation was conducted to determine the prevalence rate of Jordanian children born with oral clefts from 1991 to 2001.

SETTING

Hospital surgical records from two main sources were used to identify all children born with orofacial clefting. Information about date of birth, sex, cleft types, and associated major anomalies and syndromes were recorded.

RESULTS

The overall prevalence rate for live births with cleft lip, cleft palate, or both was 1.39 per 1000 live births. Thirty percent of the clefts identified affected the lip, 22 percent affected the palate, and 48 percent involved the clefts of the lip and palate. In general, higher prevalence rates were found for boys than girls (55% boys versus 45% girls). There was a statistically significant sex difference between the cleft types. Clefts of the isolated palate, however, were more common in girls. Eighteen percent of patients with cleft were associated with major anomalies or syndromes.

CONCLUSIONS

The reported prevalence rate for orofacial clefts among Jordanians is similar to the previously reported prevalence rate in white Caucasians. Results and future recommendations are discussed.

摘要

目的与设计

开展一项回顾性调查,以确定1991年至2001年约旦出生时患有口腔腭裂的儿童的患病率。

背景

利用来自两个主要来源的医院手术记录来确定所有出生时患有口面部裂的儿童。记录了出生日期、性别、腭裂类型以及相关的主要异常和综合征的信息。

结果

唇裂、腭裂或两者皆有的活产婴儿总体患病率为每1000例活产1.39例。所确定的腭裂中,30%影响唇部,22%影响腭部,48%涉及唇腭裂。一般而言,男孩的患病率高于女孩(男孩占55%,女孩占45%)。腭裂类型之间存在统计学上显著的性别差异。然而,单纯腭裂在女孩中更为常见。18%的腭裂患者伴有主要异常或综合征。

结论

约旦人面部腭裂的报告患病率与先前报告的白种人患病率相似。讨论了结果及未来建议。

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