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术中地形图引导的定制光治疗性角膜切削术。

Custom phototherapeutic keratectomy with intraoperative topography.

作者信息

Vinciguerra Paolo, Camesasca Fabrizio I

机构信息

Department of Ophthalmology, Istituto Clinico Humanitas, Rozzano-Milano, Italy.

出版信息

J Refract Surg. 2004 Sep-Oct;20(5):S555-63.

Abstract

PURPOSE

Treatment of highly aberrated eyes with opacities or irregularities consequent to previous refractive treatment, ulcers, keratitis, trauma, or corneal dystrophies remains a challenge for refractive surgeons. We evaluated the results of custom phototherapeutic keratectomy (CPK) with intraoperative corneal topography-based aberrometry and custom ablation in highly aberrated eyes.

METHODS

We prospectively evaluated eyes undergoing custom phototherapeutic keratectomy (CPK) with custom ablation for corneal opacities and/or irregularities due to previous refractive treatment, keratitis, trauma, or dystrophies. Customization was planned according to corneal topography-based aberrometry, performed intraoperatively after removal of corneal epithelium.

RESULTS

We treated 35 eyes of 34 patients. Mean preoperative haze was 1.6 +/- 1.4 in eyes with previous refractive surgery. Mean preoperative pachymetry was 425.7 +/- 119.3 microm. Mean preoperative spherical equivalent refraction was -1.60 +/- 3.65 D ranging from -9.38 to +10.00 D. No eye reached 20/15 best spectacle-corrected visual acuity (BSCVA), and only 63% could see 20/30 BSCVA. At final 6-month examination, mean spherical equivalent refraction was -0.71 +/- 4.01 D, ranging from -11.25 to +5.25 D. All eyes reached 20/30 or better BSCVA, and 19% had 20/15 or better BSCVA.

CONCLUSIONS

Intraoperative, epithelium-free topography-based corneal aberrometry proved to be a feasible option for custom ablation in highly aberrated eyes. This approach widens the applications of PTK, providing a new procedure, custom PTK, that can be a successful solution for eyes that would otherwise require penetrating keratoplasty.

摘要

目的

对于因先前屈光治疗、溃疡、角膜炎、外伤或角膜营养不良而出现混浊或不规则的高度异常眼,其治疗仍是屈光手术医生面临的一项挑战。我们评估了基于术中角膜地形图的像差测量和定制消融的定制光治疗性角膜切削术(CPK)在高度异常眼中的效果。

方法

我们前瞻性地评估了因先前屈光治疗、角膜炎、外伤或营养不良而接受定制光治疗性角膜切削术(CPK)及定制消融以治疗角膜混浊和/或不规则的眼睛。根据基于角膜地形图的像差测量进行定制规划,在去除角膜上皮后于术中进行。

结果

我们治疗了34例患者的35只眼。先前接受过屈光手术的眼中,术前平均 haze 为1.6±1.4。术前平均角膜厚度为425.7±119.3微米。术前平均球镜等效屈光度为 -1.60±3.65 D,范围从 -9.38至 +10.00 D。没有眼睛达到最佳矫正视力(BSCVA)20/15,只有63%的眼睛能看到BSCVA 20/30。在最后6个月的检查中,平均球镜等效屈光度为 -0.71±4.01 D,范围从 -11.25至 +5.25 D。所有眼睛均达到BSCVA 20/30或更好,19%的眼睛达到BSCVA 20/15或更好。

结论

术中无上皮的基于地形图的角膜像差测量被证明是高度异常眼中定制消融的一种可行选择。这种方法拓宽了PTK的应用范围,提供了一种新的手术方法——定制PTK,对于那些否则需要穿透性角膜移植的眼睛来说可能是一种成功的解决方案。

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