Thomas Hollie V, Lewis Glyn, Watson Margaret, Bell Truda, Lyons Ita, Lloyd Keith, Weich Scott, Sharp Deborah
Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK.
Br J Gen Pract. 2004 Nov;54(508):832-7.
A large proportion of people with depression and anxiety go unrecognised by their general practitioner (GP). Case-finding does not appear to be effective on its own.
To compare the effectiveness of case-finding followed by computer-generated patient-specific guidelines with usual care for the management of common mental disorders in primary care.
Individual patient randomised controlled trial.
Five general practices in Bristol and Cardiff.
762 individuals aged >/= 16 years scoring >/= 12 on the Clinical Interview Schedule Revised were randomised. The experimental intervention required participants to complete a computerised psychosocial assessment that generated a report for the GP including patient-specific treatment recommendations. The control patients were treated as usual with access to locally agreed guidelines.
Participants' 12-item General Health Questionnaire (GHQ) score dropped irrespective of treatment allocation. The experimental group had a significantly lower GHQ score at 6 weeks, but not at 6 months. Recovery at 6 months was 3% greater among those receiving the experimental intervention (95% confidence interval [CI] = -4 to 10). Treatment was not significantly associated with quality of life or patient satisfaction.
Only small benefits are likely from using case-finding followed by patient-specific guidelines to improve clinical management of common mental disorders in primary care. However, depression and anxiety are important public health problems so the utility of such systems should be further investigated.
很大一部分抑郁症和焦虑症患者未被其全科医生(GP)识别出来。仅靠病例筛查似乎效果不佳。
比较在初级医疗中,病例筛查后结合计算机生成的针对患者的指南与常规护理对常见精神障碍管理的有效性。
个体患者随机对照试验。
布里斯托尔和加的夫的五家全科诊所。
将762名年龄≥16岁且在修订版临床访谈量表上得分≥12分的个体随机分组。实验性干预要求参与者完成一项计算机化的心理社会评估,该评估会为全科医生生成一份报告,其中包括针对患者的治疗建议。对照患者接受常规治疗,并可获取当地商定的指南。
无论治疗分配如何,参与者的12项一般健康问卷(GHQ)得分均有所下降。实验组在6周时的GHQ得分显著较低,但在6个月时并非如此。接受实验性干预的患者在6个月时的康复率高出3%(95%置信区间[CI]=-4至10)。治疗与生活质量或患者满意度无显著关联。
在初级医疗中,采用病例筛查后结合针对患者的指南来改善常见精神障碍的临床管理,可能只会带来微小的益处。然而,抑郁症和焦虑症是重要的公共卫生问题,因此此类系统的效用应进一步研究。