Dopazo J
Centro de Investigacioń en Sanidad Animal, INIA, Madrid, Spain.
J Mol Evol. 1994 Mar;38(3):300-4. doi: 10.1007/BF00176092.
A method, based on the bootstrap procedure, is proposed for the estimation of branch-length errors and confidence intervals in a phylogenetic tree for which equal rates of substitution among lineages do not necessarily hold. The method can be used to test whether an estimated internodal distance is significantly greater than zero. In the application of the method, any estimator of genetic distances, as well as any tree reconstruction procedure (based on distance matrices), can be used. Also the method is not limited by the number of species involved in the phylogenetic tree. An example of the application of the method in the reconstruction of the phylogenetic tree for the four hominoid species--human, chimpanzee, gorilla, and orangutan--is shown.
提出了一种基于自展程序的方法，用于估计系统发育树中的分支长度误差和置信区间，该系统发育树中各谱系的替代率不一定相等。该方法可用于检验估计的节点间距离是否显著大于零。在该方法的应用中，可以使用任何遗传距离估计器以及任何（基于距离矩阵的）树重建程序。而且该方法不受系统发育树中所涉及物种数量的限制。展示了该方法在重建人类、黑猩猩、大猩猩和猩猩这四种类人猿物种的系统发育树中的应用示例。
