Carter Elliot, Boudreaux Carole
Department of Pathology, University of South Alabama, Mobil, AL 36617, USA.
J Clin Microbiol. 2004 Nov;42(11):5419-23. doi: 10.1128/JCM.42.11.5419-5423.2004.
Curvularia infections in humans are relatively uncommon despite the ubiquitous presence of this soil-dwelling dematiaceous fungus in the environment. Originally thought to be solely a pathogen of plants, Curvularia has been described as a pathogen of humans and animals in the last half-century, causing respiratory tract, cutaneous, and corneal infections. Only three previous cases of central nervous system involvement by Curvularia have been documented in the medical literature. We report a fatal case of cerebral Curvularia infection in which there was no known history of immunocompromise or prior respiratory tract or sinus infection in the patient.
尽管这种土壤腐生暗色丝孢菌在环境中普遍存在，但人类感染弯孢霉相对并不常见。弯孢霉最初被认为仅是植物病原体，在过去半个世纪里已被描述为人类和动物的病原体，可引起呼吸道、皮肤和角膜感染。医学文献中仅记载过3例此前弯孢霉累及中枢神经系统的病例。我们报告1例致命的脑弯孢霉感染病例，该患者无已知的免疫功能低下病史，也无既往呼吸道或鼻窦感染史。
