Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
Guangxi Health Commission Key Lab of Fungi and Mycosis Research and Prevention (The First Affiliated Hospital of Guangxi Medical University), Nanning, 530021, China.
Mycopathologia. 2022 Jun;187(2-3):291-298. doi: 10.1007/s11046-022-00619-8. Epub 2022 Mar 4.
Tinea nigra is a superficial fungal infection usually caused by Hortaea werneckii (H. werneckii). We report a special case of tinea nigra in an immunocompetent child who developed a unilateral, rapidly growing pigmented lesion on her palm. Interestingly, Curvularia lunata (C. lunata) was isolated from the lesion scrapes and was identified by both morphological features and molecular biology methods. The lesion was completely cleared by topical naftifine hydrochloride and ketoconazole cream. We present-to the best of our knowledge-the first case of tinea nigra where the causative pathogen was identified as C. lunata. We therefore provide a brief literature review of previously reported cases of tinea nigra to broaden the knowledge of the potential causative pathogens. The etiology, demography, clinical features, diagnostic methods, and treatment of the reviewed cases are summarized and analyzed.
黑癣是一种由 Hortaea werneckii(H. werneckii)引起的浅表真菌感染。我们报告了一例免疫功能正常的儿童中发生的特殊黑癣病例,该儿童手掌上单侧出现快速生长的色素性病变。有趣的是,从病变刮片中分离出弯孢菌(C. lunata),并通过形态特征和分子生物学方法进行了鉴定。局部应用盐酸萘替芬和酮康唑乳膏后,病变完全清除。据我们所知,这是首例由弯孢菌引起的黑癣病例。因此,我们简要回顾了以往报道的黑癣病例,以拓宽对潜在病原体的认识。总结并分析了综述病例的病因、人口统计学、临床特征、诊断方法和治疗方法。