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A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics.αβ1整合素在粘着斑功能和极化细胞骨架动力学中的作用。
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Sensing the environment: a historical perspective on integrin signal transduction.感知环境：整合素信号转导的历史视角
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Exosomal integrins in tumor progression, treatment and clinical prediction (Review).外泌体整合素在肿瘤进展、治疗和临床预测中的作用（综述）。
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本文引用的文献

1
Tissue-specific modulation of a set of related cell surface antigens in Drosophila.果蝇中一组相关细胞表面抗原的组织特异性调控。
Nature. 1985 Jul 25;316(6026):351-4. doi: 10.1038/316351a0.
2
Integrins: roles in cancer development and as treatment targets.整合素：在癌症发展中的作用及作为治疗靶点
Br J Cancer. 2004 Feb 9;90(3):561-5. doi: 10.1038/sj.bjc.6601576.
3
The diverse roles of integrins and their ligands in angiogenesis.整合素及其配体在血管生成中的多种作用。
Cold Spring Harb Symp Quant Biol. 2002;67:143-53. doi: 10.1101/sqb.2002.67.143.
4
Integrin adhesion receptors in tumor metastasis.肿瘤转移中的整合素黏附受体
Clin Exp Metastasis. 2003;20(3):203-13. doi: 10.1023/a:1022983000355.
5
Integrins: bidirectional, allosteric signaling machines.整合素：双向变构信号传导机器
Cell. 2002 Sep 20;110(6):673-87. doi: 10.1016/s0092-8674(02)00971-6.
6
Integrin activation and structural rearrangement.整合素激活与结构重排。
Immunol Rev. 2002 Aug;186:141-63. doi: 10.1034/j.1600-065x.2002.18613.x.
7
Integrin activation takes shape.整合素激活初具形态。
J Cell Biol. 2002 Sep 2;158(5):833-9. doi: 10.1083/jcb.200206011. Epub 2002 Sep 3.
8
A reevaluation of integrins as regulators of angiogenesis.整合素作为血管生成调节因子的重新评估
Nat Med. 2002 Sep;8(9):918-21. doi: 10.1038/nm0902-918.
9
Conformational regulation of integrin structure and function.整合素结构与功能的构象调节
Annu Rev Biophys Biomol Struct. 2002;31:485-516. doi: 10.1146/annurev.biophys.31.101101.140922. Epub 2001 Oct 25.
10
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand.整合素αVβ3胞外段与精氨酸-甘氨酸-天冬氨酸配体复合物的晶体结构。
Science. 2002 Apr 5;296(5565):151-5. doi: 10.1126/science.1069040. Epub 2002 Mar 7.

The emergence of integrins: a personal and historical perspective.

作者信息

Hynes Richard O

机构信息

Howard Hughes Medical Institute, Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

出版信息

Matrix Biol. 2004 Oct;23(6):333-40. doi: 10.1016/j.matbio.2004.08.001.

DOI:10.1016/j.matbio.2004.08.001
PMID:15533754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3493146/
Abstract
摘要