The emergence of integrins: a personal and historical perspective.
作者信息
Hynes Richard O
机构信息
Howard Hughes Medical Institute, Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
出版信息
Matrix Biol. 2004 Oct;23(6):333-40. doi: 10.1016/j.matbio.2004.08.001.
Abstract
摘要
相似文献
1
The emergence of integrins: a personal and historical perspective.整合素的出现：个人观点与历史视角
Matrix Biol. 2004 Oct;23(6):333-40. doi: 10.1016/j.matbio.2004.08.001.
2
A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics.αβ1整合素在粘着斑功能和极化细胞骨架动力学中的作用。
Dev Cell. 2003 Sep;5(3):415-27. doi: 10.1016/s1534-5807(03)00261-2.
3
Sensing the environment: a historical perspective on integrin signal transduction.感知环境：整合素信号转导的历史视角
Nat Cell Biol. 2002 Apr;4(4):E83-90. doi: 10.1038/ncb0402-e83.
4
Integrins and the actin cytoskeleton.整合素与肌动蛋白细胞骨架
Curr Opin Cell Biol. 2007 Feb;19(1):43-50. doi: 10.1016/j.ceb.2006.12.013. Epub 2006 Dec 20.
5
Cell motility. Making connections count.细胞运动性：让连接发挥作用。
Nature. 1996 Oct 3;383(6599):390-1. doi: 10.1038/383390a0.
6
Mechanisms for organization of fibronectin matrix.
Cell Differ Dev. 1990 Dec 2;32(3):439-50. doi: 10.1016/0922-3371(90)90061-z.
7
[Integrins: the importance of cell adhesion].
Med Clin (Barc). 1990 Nov 10;95(16):630-5.
8
The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin.巨噬细胞与层粘连蛋白的激活依赖性黏附涉及细胞骨架锚定和α6β1整合素的磷酸化。
J Cell Biol. 1990 Jun;110(6):2167-74. doi: 10.1083/jcb.110.6.2167.
9
Integrating adhesion, protrusion, and contraction during cell migration.细胞迁移过程中黏附、突出和收缩的整合。
Cell. 2006 Jun 30;125(7):1223-5. doi: 10.1016/j.cell.2006.06.015.
10
Martin Humphries: Attached to adhesion. Interview by Caitlin Sedwick.马丁·汉弗莱斯：粘连的附属物。采访者：凯特琳·塞德威克。
J Cell Biol. 2013 Mar 4;200(5):554-5. doi: 10.1083/jcb.2005pi.
引用本文的文献
1
Integrins and NAFLD-associated liver diseases: clinical associations, pathophysiological mechanisms and pharmacological implications.整合素与非酒精性脂肪性肝病相关肝脏疾病：临床关联、病理生理机制及药理学意义
Acta Biochim Biophys Sin (Shanghai). 2024 Sep 14;56(11):1573-1583. doi: 10.3724/abbs.2024149.
2
Integrins as Drug Targets in Vascular and Related Diseases.整合素作为血管及相关疾病的药物靶点
Int J Drug Discov Pharm. 2024 Jun;3(2). doi: 10.53941/ijddp.2024.100010. Epub 2024 Jun 21.
3
Phagocytosis by the retinal pigment epithelium: New insights into polarized cell mechanics.视网膜色素上皮细胞的吞噬作用：极化细胞力学的新见解
Bioessays. 2025 Jan;47(1):e2300197. doi: 10.1002/bies.202300197. Epub 2024 Dec 11.
4
Exosomal integrins in tumor progression, treatment and clinical prediction (Review).外泌体整合素在肿瘤进展、治疗和临床预测中的作用（综述）。
Int J Oncol. 2024 Dec;65(6). doi: 10.3892/ijo.2024.5706. Epub 2024 Nov 14.
5
No crops without seeds: the risks in declining support for fundamental research.没有种子就没有庄稼：基础研究支持力度下降的风险。
Nat Cardiovasc Res. 2023 Mar;2(3):193-195. doi: 10.1038/s44161-023-00225-x.
6
Integrins as a bridge between bacteria and cells: key targets for therapeutic wound healing.整合素作为细菌与细胞之间的桥梁：治疗伤口愈合的关键靶点。
Burns Trauma. 2024 Jul 16;12:tkae022. doi: 10.1093/burnst/tkae022. eCollection 2024.
7
Integrins regulation of wound healing processes: insights for chronic skin wound therapeutics.整合素对伤口愈合过程的调控：慢性皮肤伤口治疗的新视角。
Front Cell Infect Microbiol. 2024 Mar 5;14:1324441. doi: 10.3389/fcimb.2024.1324441. eCollection 2024.
8
Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targets.整合素β-1在疾病与癌症中的作用：分子机制与治疗靶点
Cell Commun Signal. 2024 Jan 26;22(1):71. doi: 10.1186/s12964-023-01338-3.
9
Synthetic extracellular matrices with function-encoding peptides.具有功能编码肽的合成细胞外基质。
Nat Rev Bioeng. 2023 Apr 25:1-19. doi: 10.1038/s44222-023-00055-3.
10
Trends in mechanobiology guided tissue engineering and tools to study cell-substrate interactions: a brief review.机械生物学指导的组织工程趋势及细胞-基质相互作用研究工具：简要综述
Biomater Res. 2023 Jun 1;27(1):55. doi: 10.1186/s40824-023-00393-8.
本文引用的文献
1
Tissue-specific modulation of a set of related cell surface antigens in Drosophila.果蝇中一组相关细胞表面抗原的组织特异性调控。
Nature. 1985 Jul 25;316(6026):351-4. doi: 10.1038/316351a0.
2
Integrins: roles in cancer development and as treatment targets.整合素：在癌症发展中的作用及作为治疗靶点
Br J Cancer. 2004 Feb 9;90(3):561-5. doi: 10.1038/sj.bjc.6601576.
3
The diverse roles of integrins and their ligands in angiogenesis.整合素及其配体在血管生成中的多种作用。
Cold Spring Harb Symp Quant Biol. 2002;67:143-53. doi: 10.1101/sqb.2002.67.143.
4
Integrin adhesion receptors in tumor metastasis.肿瘤转移中的整合素黏附受体
Clin Exp Metastasis. 2003;20(3):203-13. doi: 10.1023/a:1022983000355.
5
Integrins: bidirectional, allosteric signaling machines.整合素：双向变构信号传导机器
Cell. 2002 Sep 20;110(6):673-87. doi: 10.1016/s0092-8674(02)00971-6.
6
Integrin activation and structural rearrangement.整合素激活与结构重排。
Immunol Rev. 2002 Aug;186:141-63. doi: 10.1034/j.1600-065x.2002.18613.x.
7
Integrin activation takes shape.整合素激活初具形态。
J Cell Biol. 2002 Sep 2;158(5):833-9. doi: 10.1083/jcb.200206011. Epub 2002 Sep 3.
8
A reevaluation of integrins as regulators of angiogenesis.整合素作为血管生成调节因子的重新评估
Nat Med. 2002 Sep;8(9):918-21. doi: 10.1038/nm0902-918.
9
Conformational regulation of integrin structure and function.整合素结构与功能的构象调节
Annu Rev Biophys Biomol Struct. 2002;31:485-516. doi: 10.1146/annurev.biophys.31.101101.140922. Epub 2001 Oct 25.
10
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand.整合素αVβ3胞外段与精氨酸-甘氨酸-天冬氨酸配体复合物的晶体结构。
Science. 2002 Apr 5;296(5565):151-5. doi: 10.1126/science.1069040. Epub 2002 Mar 7.
Zotero 插件