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左半结肠癌性梗阻的治疗选择

Management options in malignant obstruction of the left colon.

作者信息

MacKenzie S, Thomson S R, Baker L W

机构信息

Department of Surgery, University of Natal Medical School, Durban, Republic of South Africa.

出版信息

Surg Gynecol Obstet. 1992 Apr;174(4):337-45.

PMID:1553616
Abstract

Three of every 20 patients with carcinoma of the colon present with obstruction. The prognosis in the patient with malignant left colon obstruction is worse than for those with nonobstructing lesions, without adding the burden of a colostomy. Whenever feasible, acute obstruction should be treated by definitive resection with primary anastomosis and staged procedures reserved for only a few. How the former is achieved is open to debate. Whether or not the removal of all fecal matter from the colon is necessary before anastomosis is questionable and needs further appraisal. The risk of a metachronous lesion developing is highest in young patients with polyps or a previously resected carcinoma. The high risk patients would be best served by a subtotal colectomy. The choice of procedure must be tailored to each patient and the final decision made at the time of operation. An experienced colonic surgeon is needed to judge which option is most appropriate.

摘要

每20例结肠癌患者中有3例出现肠梗阻。左半结肠癌伴恶性梗阻患者的预后比无梗阻性病变的患者更差,且无需承受结肠造口术的负担。只要可行,急性梗阻应通过一期切除吻合术进行确定性治疗,分期手术仅适用于少数患者。如何实现前者仍存在争议。吻合术前是否有必要清除结肠内所有粪便值得怀疑,需要进一步评估。息肉患者或既往有结肠癌切除术的年轻患者发生异时性病变的风险最高。对于高危患者,次全结肠切除术是最佳选择。手术方式的选择必须根据每个患者的情况量身定制,并在手术时做出最终决定。需要经验丰富的结肠外科医生来判断哪种选择最合适。

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