Uhlén Per
Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520-8066, USA.
Sci STKE. 2004 Nov 9;2004(258):pl15. doi: 10.1126/stke.2582004pl15.
Calcium (Ca2+) oscillations are universal signals exploited by cells to regulate a vast number of cellular processes. Frequency and amplitude, the key features of oscillating waves, can yield information that can be decoded by intracellular processes. Analysis and quantification of Ca2+ oscillations are crucial for understanding the general concept of Ca2+ signaling. This protocol presents a method for performing spectral analysis of Ca2+ oscillations using MATLAB software.
钙离子(Ca2+)振荡是细胞用于调节大量细胞过程的通用信号。振荡波的关键特征——频率和振幅,能够产生可被细胞内过程解码的信息。Ca2+振荡的分析和量化对于理解Ca2+信号传导的一般概念至关重要。本方案介绍了一种使用MATLAB软件对Ca2+振荡进行频谱分析的方法。