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逼尿肌平滑肌动作电位分析

Analysis of the detrusor smooth muscle action potential.

作者信息

Karim O M, Seki N, Mostwin J L

机构信息

James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland.

出版信息

Urol Res. 1992;20(2):173-6. doi: 10.1007/BF00296533.

DOI:10.1007/BF00296533
PMID:1553794
Abstract

A method is described to record bladder smooth muscle action potential (AP) data and subsequently in digitized form analyze the constitutive elements of the AP. Manipulation of digitized data can give accurate descriptive information on the AP configuration and kinetics. In the future this type of analysis will hopefully lead to more precise, quantitative information on changes in the smooth muscle AP kinetics with disease states and facilitate a clearer understanding of the pathophysiological processes underlying changes in detrusor contractility.

摘要

本文描述了一种记录膀胱平滑肌动作电位(AP)数据并随后以数字化形式分析AP组成成分的方法。对数字化数据的处理能够提供关于AP形态和动力学的准确描述信息。未来,这种分析类型有望获得关于疾病状态下平滑肌AP动力学变化的更精确、定量的信息,并有助于更清晰地理解逼尿肌收缩力变化背后的病理生理过程。

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引用本文的文献

1
Changes in action potential kinetics following experimental bladder outflow obstruction in the guinea pig.豚鼠实验性膀胱出口梗阻后动作电位动力学的变化。
Urol Res. 1992;20(6):387-92. doi: 10.1007/BF00294493.

本文引用的文献

1
Changes in contractile properties in hypertrophic rat urinary bladder.肥厚型大鼠膀胱收缩特性的变化
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