Roujeau Jean-Claude, Sigurgeirsson Bardur, Korting Hans-Christian, Kerl Helmut, Paul Carle
Service de Dermatologie, Hôpital Henri-Mondor, Créteil, France.
Dermatology. 2004;209(4):301-7. doi: 10.1159/000080853.
To assess the role of foot dermatomycosis (tinea pedis and onychomycosis) and other candidate risk factors in the development of acute bacterial cellulitis of the leg.
A case-control study, including 243 patients (cases) with acute bacterial cellulitis of the leg and 467 controls, 2 per case, individually matched for gender, age (+/-5 years), hospital and admission date (+/-2 months).
Overall, mycology-proven foot dermatomycosis was a significant risk factor for acute bacterial cellulitis (odds ratio, OR: 2.4; p < 0.001), as were tinea pedis interdigitalis (OR: 3.2; p < 0.001), tinea pedis plantaris (OR: 1.7; p = 0.005) and onychomycosis (OR: 2.2; p < 0.001) individually. Other risk factors included: disruption of the cutaneous barrier, history of bacterial cellulitis, chronic venous insufficiency and leg oedema.
Tinea pedis and onychomycosis were found to be significant risk factors for acute bacterial cellulitis of the leg that are readily amenable to treatment with effective pharmacological therapy.
评估足部皮肤癣菌病（足癣和甲癣）及其他潜在危险因素在腿部急性细菌性蜂窝织炎发病中的作用。
一项病例对照研究，纳入243例腿部急性细菌性蜂窝织炎患者（病例组）和467例对照，每例病例匹配2名对照，根据性别、年龄（±5岁）、医院及入院日期（±2个月）进行个体匹配。
总体而言，经真菌学证实的足部皮肤癣菌病是急性细菌性蜂窝织炎的显著危险因素（比值比，OR：2.4；p<0.001），指间足癣（OR：3.2；p<0.001）、跖部足癣（OR：1.7；p = 0.005）及甲癣（OR：2.2；p<0.001）单独来看也是危险因素。其他危险因素包括：皮肤屏障破坏、细菌性蜂窝织炎病史、慢性静脉功能不全及腿部水肿。
足癣和甲癣是腿部急性细菌性蜂窝织炎的显著危险因素，通过有效的药物治疗易于控制。
