Dhalla Shayesta
University of British Columbia, Vancouver, BC.
Can J Surg. 2004 Oct;47(5):375-9.
The incidence of tetanus declined dramatically in the 20th century owing to routine vaccination and prompt attention to wound care. Postsurgical tetanus is uncommon, with both exogenous and endogenous sources being responsible for disease. The majority of cases of postoperative tetanus have been observed after intra-abdominal surgery. Those at high risk for developing tetanus include immigrants, the elderly, injection drug users, patients with diabetes and people of Hispanic ethnicity. Although most patients with tetanus can recover if managed appropriately, prevention through active and passive immunization is the main goal. This paper reviews postsurgical tetanus and provides an approach to its prevention and treatment.
由于常规疫苗接种以及对伤口护理的及时关注,破伤风的发病率在20世纪急剧下降。术后破伤风并不常见,外源性和内源性因素均可导致发病。大多数术后破伤风病例见于腹部手术之后。破伤风的高危人群包括移民、老年人、注射吸毒者、糖尿病患者以及西班牙裔人群。尽管多数破伤风患者若得到恰当治疗能够康复,但通过主动和被动免疫进行预防仍是主要目标。本文对术后破伤风进行综述,并提供其预防和治疗方法。