Deshaies Eric M, Adamo Matthew A, Qian Jiang, DiRisio Darryl A
Department of Surgery, Division of Neurosurgery, Albany Medical Center, Albany, New York 12208, USA.
J Neurosurg. 2004 Nov;101(5):858-60. doi: 10.3171/jns.2004.101.5.0858.
This 79-year-old woman presented with progressively worsening dementia, abulia, flat affect, urinary incontinence, and profuse watery diarrhea. Results of computerized tomography and magnetic resonance studies indicated an extraaxial, dural-based mass compressing the right frontal lobe and consistent with a convexity meningioma. A right frontal craniotomy was performed and the dural-based mass was resected. Histopathological features on immunostaining of the lesion were consistent with a carcinoid tumor (low-grade neuroendocrine carcinoma). Further evaluation revealed no primary carcinoid tumor in the foregut from which they typically originate. The authors concluded that this intracranial carcinoid tumor was the primary lesion despite its unusual location and that it should be included in the differential diagnosis of dural-based, extraaxial brain lesions.
这位79岁女性出现进行性加重的痴呆、意志缺失、情感淡漠、尿失禁和大量水样腹泻。计算机断层扫描和磁共振检查结果显示，一个位于轴外、硬膜下的肿块压迫右侧额叶，与凸面脑膜瘤相符。进行了右侧额叶开颅手术，并切除了硬膜下肿块。病变免疫染色的组织病理学特征与类癌（低级别神经内分泌癌）一致。进一步评估未发现它们通常起源的前肠存在原发性类癌肿瘤。作者得出结论，尽管该颅内类癌肿瘤位置不寻常，但它是原发性病变，在硬膜下轴外脑病变的鉴别诊断中应予以考虑。
