许多P因子插入会影响黑腹果蝇的翅膀形状。
Many P-element insertions affect wing shape in Drosophila melanogaster.
作者信息
Weber Kenneth, Johnson Nancy, Champlin David, Patty April
机构信息
Department of Biological Sciences, University of Southern Maine, Portland, 04104-9300, USA.
出版信息
Genetics. 2005 Mar;169(3):1461-75. doi: 10.1534/genetics.104.027748. Epub 2004 Nov 15.
Abstract
A screen of random, autosomal, homozygous-viable P-element insertions in D. melanogaster found small effects on wing shape in 11 of 50 lines. The effects were due to single insertions and remained stable and significant for over 5 years, in repeated, high-resolution measurements. All 11 insertions were within or near protein-coding transcription units, none of which were previously known to affect wing shape. Many sites in the genome can affect wing shape.
摘要
对黑腹果蝇中随机、常染色体、纯合存活的P因子插入进行筛选，发现50个品系中有11个品系的翅形受到微小影响。这些影响是由单个插入引起的，并且在重复的高分辨率测量中，5年多来一直保持稳定且显著。所有11个插入都在蛋白质编码转录单元内或附近，其中没有一个先前已知会影响翅形。基因组中的许多位点都能影响翅形。
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