鼓室内类固醇治疗：综述
Intratympanic steroid treatment: a review.
作者信息
Doyle Karen Jo, Bauch Christopher, Battista Robert, Beatty Charles, Hughes Gordon B, Mason John, Maw Jennifer, Musiek Frank L
机构信息
Department of Otolaryngology--Head and Neck Surgery, University of California Davis, Sacramento, California 95817, USA.
出版信息
Otol Neurotol. 2004 Nov;25(6):1034-9. doi: 10.1097/00129492-200411000-00031.
OBJECTIVE
To review published literature regarding the use of intratympanic steroids in the treatment of Meniere's disease and sudden sensorineural hearing loss and to make recommendations regarding their use based on the literature review.
DATA SOURCES
Literature review from 1996 to 2003, PubMed, Medline Plus, and Web of Science.
STUDY SELECTION
Retrospective case series and uncontrolled prospective cohort studies were the only types of studies available for review.
CONCLUSION
On the basis of the available literature, a weak recommendation is made to use intratympanic steroid treatment of sudden hearing loss if oral steroid therapy fails or is contraindicated. The available studies regarding intratympanic steroid treatment of Meniere's disease and tinnitus are inadequate to answer the question of the efficacy of this treatment for these conditions. Higher quality studies are needed.
目的
回顾已发表的关于鼓室内注射类固醇治疗梅尼埃病和突发性感音神经性听力损失的文献，并根据文献综述对其使用提出建议。
资料来源
1996年至2003年的文献综述、PubMed、Medline Plus和科学网。
研究选择
回顾的研究类型仅包括回顾性病例系列研究和非对照前瞻性队列研究。
结论
根据现有文献，如果口服类固醇治疗失败或有禁忌，对于突发性听力损失采用鼓室内注射类固醇治疗可给出弱推荐。关于鼓室内注射类固醇治疗梅尼埃病和耳鸣的现有研究不足以回答该治疗对这些病症疗效的问题。需要更高质量的研究。
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