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Photohemolysis of erythrocytes by He-Ne laser irradiation: the effect of power density.

作者信息

Cen Y, Chen J Y

机构信息

Department of Physics, Fudan University, Shanghai 200433, China.

出版信息

Lasers Med Sci. 2004;19(3):161-4. doi: 10.1007/s10103-004-0320-z. Epub 2004 Nov 12.

DOI:10.1007/s10103-004-0320-z
PMID:15549580
Abstract

The effects of He-Ne laser irradiation on erythrocyte hemolysis were studied. Erythrocytes are prone to be easily damaged with hemolysis under laser irradiation. It was found that the power density (PD) of laser irradiation, but not the total irradiation power, is the crucial parameter for the hemolysis. Under irradiation with a PD of 5.41 mW/microm(2), erythrocytes were photohemolyzed within a few seconds, while at a PD of 0.52 mW/microm(2) the average tolerance duration (TD; from the start of irradiation to hemolysis) of erythrocytes was 110 s. The TDs of erythrocytes were also individual erythrocyte-dependent, which may be due to their different ages. The average TDs of erythrocyte samples from different donors were different, reflecting individual variations.

摘要

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本文引用的文献

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A comparative study of 632.8 and 532 nm laser irradiation on some rheological factors in human blood in vitro.632.8纳米和532纳米激光体外照射对人体血液某些流变学因素的比较研究。
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Power density and exposure time of He-Ne laser irradiation are more important than total energy dose in photo-biomodulation of human fibroblasts in vitro.在体外对人成纤维细胞进行光生物调节时,氦氖激光照射的功率密度和照射时间比总能量剂量更为重要。
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