钯催化的亚砜亚胺的N-乙烯基化反应。
Palladium-catalyzed N-vinylation of sulfoximines.
作者信息
Dehli Juan R, Bolm Carsten
机构信息
Institut für Organische Chemie der RWTH Aachen, Professor-Pirlet-Str. 1, D-52056 Aachen, Germany.
出版信息
J Org Chem. 2004 Nov 26;69(24):8518-20. doi: 10.1021/jo0485583.
PMID:15549834
Abstract
New previously unavailable N-vinyl sulfoximines have been synthesized by intermolecular palladium-catalyzed coupling between sulfoximines and vinyl bromides in excellent yield. Hydrogenation of the vinyl moiety opens a novel way to alpha-branched N-alkyl sulfoximines.
摘要
通过亚砜亚胺与溴乙烯之间的分子间钯催化偶联反应，已合成出了新型的、以前无法获得的N-乙烯基亚砜亚胺，产率极高。乙烯基部分的氢化反应为α-支链N-烷基亚砜亚胺开辟了一条新途径。
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