Arlet J
Universite Paul Sabatier, Toulouse, France.
Clin Orthop Relat Res. 1992 Apr(277):12-21.
The history of research on avascular necrosis of the femoral head during the past 30 years includes clinical and radiologic data, etiology and epidemiology, histopathology, and other methods of exploration, pathophysiology and pathogenesis, and treatments. Preradiologic stages of the disease, its association with corticosteroid treatment, the use of core biopsy and magnetic resonance imaging for an early diagnosis, the pathogenetic significance of increased intramedullary pressure and of lipid metabolism and fat cell changes, and conservative surgical procedures such as core decompression and rotational osteotomy constitute important areas for further investigation as outlined in detail in this review.
过去30年中关于股骨头缺血性坏死的研究历史涵盖了临床和放射学数据、病因学和流行病学、组织病理学以及其他探索方法、病理生理学和发病机制，还有治疗方法。该疾病的放射学前阶段、其与皮质类固醇治疗的关联、使用核心活检和磁共振成像进行早期诊断、髓内压升高以及脂质代谢和脂肪细胞变化的发病学意义，以及诸如核心减压和旋转截骨术等保守手术程序，构成了本综述详细概述的进一步研究的重要领域。
