延安汉族人群15个短串联重复序列基因座的多态性
[Polymorphisms on 15 STR loci of Han population in Yan'an].
作者信息
Wang Zhen-yuan, Wang Fang, Yu Rong-jun, Li Tao, He Guang-she, Fang Jun-bang
机构信息
Department of Forensic Science, Medical College of Xi'an Jiaotong University, Xi'an 710061, China.
出版信息
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Oct;26(5):549-53.
OBJECTIVE
To investigate the polymorphisms of 15 STR loci of Han population in Yan'an.
METHODS
Blood samples were obtained from 100 unrelated Han individuals in Yan'an. DNA templates were screened by AmpF/STR Identifiler kit and ABI3100Avant DNA analyzer.
RESULTS
The allele frequencies of 15 STR loci ranged from 0.005 to 0.550, and the genotype frequencies ranged from 0.010 to 0.310. The combined match probability was 2.5x10(-17) and combined EPP was 0.999999999.
CONCLUSIONS
The 15 STR loci used in this study were highly polymorphic in Han population in Yan'an and suitable for population study and forensic cases in this region.
目的
研究延安汉族人群15个STR基因座的多态性。
方法
采集100名延安汉族无关个体的血样。采用AmpF/STR Identifiler试剂盒和ABI3100Avant DNA分析仪筛选DNA模板。
结果
15个STR基因座的等位基因频率范围为0.005至0.550，基因型频率范围为0.010至0.310。累积匹配概率为2.5×10（-17），累积个体识别率为0.999999999。
结论
本研究中使用的15个STR基因座在延安汉族人群中具有高度多态性，适用于该地区的群体研究和法医学案件。
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