Mogensen Klaus B, Klank Henning, Kutter Jörg P
MIC--Department of Micro and Nanotechnology, Technical University of Denmark, Lyngby, Denmark.
Electrophoresis. 2004 Nov;25(21-22):3498-512. doi: 10.1002/elps.200406108.
Microfluidic systems have become more and more important in the field of analytical chemistry. Detection methods on these microsystems are essential for the identification and quantification of chemical species that are being analyzed. This review concentrates on the latest developments of optical detection methods and mass spectrometry in conjunction with microfluidic systems. Electrochemical methods are discussed in another review in the same issue of this journal. Within the optical detection section, topics such as multiplexed detection and the use of waveguides are discussed. Within the discussion of mass spectrometry, the main focus is on electrospray emitters as interfaces between microsystem and spectrometer. Apart from optical detection and mass spectrometry, other techniques such as flame ionization and nuclear magnetic resonance are also mentioned.
微流控系统在分析化学领域变得越来越重要。这些微系统上的检测方法对于所分析化学物质的识别和定量至关重要。本综述集中于光学检测方法和与微流控系统相结合的质谱的最新进展。电化学方法在本期刊同一期的另一篇综述中讨论。在光学检测部分，讨论了诸如多重检测和波导的使用等主题。在质谱的讨论中，主要重点是作为微系统与光谱仪之间接口的电喷雾发射器。除了光学检测和质谱外，还提到了其他技术，如火焰离子化和核磁共振。
