Sritipsukho Paskorn
Pediatric Department, Faculty of Medicine, Thammasat University Rangsit Center, Patumthani 12121, Thailand.
Asian Pac J Allergy Immunol. 2004 Jun-Sep;22(2-3):91-5.
One hundred and twenty patients, aged 3-15 years, attending the Allergy Clinic, Thammasat University Hospital, with allergic rhinitis, asthma or both conditions were studied. Standardized skin prick tests were performed with 15 common aeroallergens. The subjects were 85 boys and 35 girls with the mean age of 8.1 years (SD = 3.4 years). There were 63 cases (53%), 22 cases (18%) and 35 cases (29%) diagnosed with allergic rhinitis only, asthma only and both conditions, respectively. The prevalence of asthma among the allergic rhinitis patients was 36 percent whereas the prevalence of allergic rhinitis among the asthmatic patients was 61 percent. The sensitization patterns for major aeroallergens among the three groups were similar with the most common sensitized allergens as D. pteronyssinus, followed by D. farinae, American cockroach, Kopok and German cockroach, respectively. Among the atopic patients, a greater number of allergen reactivity was significantly associated with the increased risk of having their coexistence of allergic rhinitis and asthma (p = 0.0046; score test for trend of odds ratio).
对120名年龄在3至15岁之间、前往泰国法政大学医院过敏诊所就诊的过敏性鼻炎、哮喘或两种疾病都有的患者进行了研究。使用15种常见的气传变应原进行标准化皮肤点刺试验。研究对象为85名男孩和35名女孩,平均年龄8.1岁(标准差=3.4岁)。仅诊断为过敏性鼻炎的有63例(53%),仅诊断为哮喘的有22例(18%),两种疾病都有的有35例(29%)。过敏性鼻炎患者中哮喘的患病率为36%,而哮喘患者中过敏性鼻炎的患病率为61%。三组中主要气传变应原的致敏模式相似,最常见的致敏变应原依次为粉尘螨、屋尘螨、美洲大蠊、可可和德国小蠊。在特应性患者中,变应原反应性数量较多与过敏性鼻炎和哮喘共存风险增加显著相关(p=0.0046;优势比趋势的计分检验)。