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[严重孕产妇贫血与妊娠结局]

[Severe maternal anemia and pregnancy outcome].

作者信息

El Guindi W, Pronost J, Carles G, Largeaud M, El Gareh N, Montoya Y, Arbeille P

机构信息

Service de Gynécologie-Obstétrique, Centre Hospitalier Franck Joly, 97320 Saint-Laurent-du-Maroni, Guyane, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2004 Oct;33(6 Pt 1):506-9. doi: 10.1016/s0368-2315(04)96563-5.

Abstract

OBJECTIVES

The aim of this study was to determine the effects of severe antenatal maternal anemia on pregnancy outcome.

MATERIAL

and methods. A retrospective study comparing 2 groups of pregnant women: 111 (pregnant women) with anemia (Hb < 8 g/dl), 111 non- anemic pregnant women (Hb >10 g/dl). Clinical and biological characteristics for both groups were compared. Data on the newborn babies were collected.

RESULTS

In the anemic group: iron deficiency was the most common cause of anemia (92.7%). There was no significant difference between the 2 groups with respect to age or parity. Maternal anemia was found to be significantly associated with more frequent preterm birth (29.2% vs 9.2%) and increased low birth weight (2933 g vs 3159 g).

DISCUSSION

The literature is not conclusive on the influence of anemia in pregnant women. More frequent preterm birth and low birth weight have been reported in the majority of studies considering mild to moderate maternal anemia (in contrast to our study where the mothers had severe anemia). Many studies indicated that routine iron supplementation during pregnancy may have beneficial effects on pregnancy outcome. Severe anemia in pregnancy may have adverse effects for the newborn and should be treated or prevented early in pregnancy.

摘要

目的

本研究旨在确定产前严重母体贫血对妊娠结局的影响。

材料与方法

一项回顾性研究,比较两组孕妇:111名贫血孕妇(血红蛋白<8 g/dl)和111名非贫血孕妇(血红蛋白>10 g/dl)。比较两组的临床和生物学特征。收集新生儿的数据。

结果

贫血组:缺铁是贫血最常见的原因(92.7%)。两组在年龄或产次方面无显著差异。发现母体贫血与更频繁的早产(29.2%对9.2%)和低出生体重增加(2933克对3159克)显著相关。

讨论

关于孕妇贫血的影响,文献尚无定论。大多数考虑轻度至中度母体贫血的研究报告了更频繁的早产和低出生体重(与我们的研究不同,我们研究中的母亲患有严重贫血)。许多研究表明,孕期常规补充铁剂可能对妊娠结局有有益影响。孕期严重贫血可能对新生儿有不良影响,应在孕期早期进行治疗或预防。

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